Objetivo: Estudar, prospectivamente, os fatores prognósticos de pacientes com hemorragia talâmica (HT). Métodos: Foram estudados os aspectos clínicos e tomográficos de 35 pacientes, internados no Hospital João Alves Filho, Aracaju, SE, entre agosto de 2004 e julho de 2005. Na análise estatística dos dados obtidos, foi considerado significante o valor p < 0,05. Foi utilizado teste ANOVA com pós-teste de Tukey e regressão linear. Resultados: Houve predominância do sexo feminino (63%); as idades variaram entre 46 e 84 anos com média de 64,5. A principal etiologia foi hipertensão arterial (85%) e o mais importante fator de risco vascular foi o diabetes melito (57%). O quadro clínico predominante foi cefaléia acompanhada de alterações do nível de consciência e déficit motor e sensitivo. A projeção talâmica mais acometida foi a direita (60%) e o território vascular mais envolvido foi o póstero-lateral (46%). Hematomas grandes (volume ≥ 20 cm3) foram mais freqüentes (71%). Conclusões: Na curva de regressão linear verificou-se relação significante entre o volume do hematoma e a idade do paciente. A análise estatística permitiu concluir existência de significância ao se correlacionar volume do HT e sua localização (p < 0,0001), volume do HT e quadro clínico (p < 0,0001), idade e gravidade do quadro clínico (p < 0,0001), prognóstico e volume do HT (p < 0,0001) e prognóstico e idade do paciente (p = 0,0004)._________________________________________________________________________________________ ABSTRACT: Objective: Prospective study of prognostic factors of patients with thalamic hemorrhage (TH). Methods: The clinical aspects and computed tomography of 35 patients, admitted in the Hospital João Alves Filho, Aracajú, Sergipe, Brazil, between August, 2004 and July, 2005 were analyzed. The results were considered significant when p < 0.05. It was used ANOVA with Tukey’s post-tests and linear regression curve. Results: A female predominance was observed (63%); the the patient’s ages varied between 46 and 84 years with average of 64.5. The main etiology of TH was arterial hypertension (85%) and the most important factor of vascular risk was the diabetes mellitus (57%). The predominant clinical manifestation was the association of headache, alterations of the conscience level and motor and sensitive deficit. The HT predominated on the right (60%) and the more involved vascular territory was the posterolateral (46%). Bigger hematomas (volume ≥ 20 cm3) were more frequent (71%) than the smaller. Conclusions: The linear regression curve showed significant relation between the volume of the hematoma and the age of the patient. The statistical analysis allowed to conclude the existence of significance when correlating the volume of the HT and its localization (p < 0.0001), volume of the HT and clinical picture (p < 0.0001), age and gravity of the clinical picture (p < 0.0001), prognosis and volume of HT (P < 0.0001) and prognosis and age of the patient (p = 0.0004).Objective: Prospective study of prognostic factors of patients with thalamic hemorrhage (TH). Methods: The clinical aspects and computed tomography of 35 patients, admitted in the Hospital João Alves Filho, Aracajú, Sergipe, Brazil, between August, 2004 and July, 2005 were analyzed. The results were considered significant when p < 0.05. It was used ANOVA with Tukey’s post-tests and linear regression curve. Results: A female predominance was observed (63%); the the patient’s ages varied between 46 and 84 years with average of 64.5. The main etiology of TH was arterial hypertension (85%) and the most important factor of vascular risk was the diabetes mellitus (57%). The predominant clinical manifestation was the association of headache, alterations of the conscience level and motor and sensitive deficit. The HT predominated on the right (60%) and the more involved vascular territory was the posterolateral (46%). Bigger hematomas (volume ≥ 20 cm3) were more frequent (71%) than the smaller. Conclusions: The linear regression curve showed significant relation between the volume of the hematoma and the age of the patient. The statistical analysis allowed to conclude the existence of significance when correlating the volume of the HT and its localization (p < 0.0001), volume of the HT and clinical picture (p < 0.0001), age and gravity of the clinical picture (p < 0.0001), prognosis and volume of HT (P < 0.0001) and prognosis and age of the patient (p = 0.0004).