Artigo
Microsurgical treatment of patients with refractory epilepsy and mesial temporal cavernous malformations: clinical experience of a tertiary epilepsy center
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2152-7806
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Autor
Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Pereira, Carlos Umberto
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
Institución
Resumen
Background: Mesiotemporal cavernous malformation can occur in 10–20% of
patients with cerebral cavernomas and are frequently associated with refractory.
Methods: A retrospective investigation was performed in the epilepsy clinic of a
Brazilian tertiary referral epilepsy center, from January 2000 to March 2012.
Results: A total of 21 patients were included in the study. Thirteen patients (62%)
evolved to Engel I; 5 (24%) to Engel II, 2 (10%) to Engel III, and 1 (5%) to Engel
IV. We observed that 10 (48%) patients with 12 years or less of epilepsy duration
evolved to Engel I and 1 (5%) to Engel II; whereas from a total of 10 patients with
epilepsy duration of more than 12 years, 3 (30%) evolved to Engel I and 7 (70%)
to Engel II, III, or IV (P < 0.001 [bilateral]; P1 ≠ P2).
Conclusion: Postsurgical seizure outcome for temporal lobe epilepsy associated
with mesiotemporal cavernomas is very satisfactory.