Artigo
Activity of Debaryomyces hansenii UFV-1 a-galactosidases against a-D-galactopyranoside derivatives
Autor
Rezende, Sebastião T. de
Viana, Pollyanna A.
Alves, Arianne de A.
Manfrini, Rozângela M.
Alves, Ricardo J.
Bemquerer, Marcelo P.
Santoro, Marcelo M.
Guimarães, Valéria M.
Institución
Resumen
α-d-Galactopyranosides were synthesized and their inhibitory activities toward the Debaryomyces hansenii UFV-1 extracellular and intracellular α-galactosidases were evaluated. Methyl α-d-galactopyranoside was the most potent inhibitor compared to the others tested, with values of 0.82 and 1.12 mmol L−1, for extracellular and intracellular enzymes, respectively. These results indicate that the presence of a hydroxyl group in the C-6 position of α-d-galactopyranoside derivatives is important for the recognition by D. hansenii UFV-1 α-galactosidases.