Brasil
| Article
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
Registro en:
GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.
0074-0276
Autor
Gadelha, Sandra Rocha
Shindo, Nice
Cruz, José Napoleão Monte
Morgado, Mariza Gonçalves
Castro Filho, Bernardo Galvão
Resumen
We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B. In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.