Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil

dc.creatorGadelha, Sandra Rocha
dc.creatorShindo, Nice
dc.creatorCruz, José Napoleão Monte
dc.creatorMorgado, Mariza Gonçalves
dc.creatorCastro Filho, Bernardo Galvão
dc.date2012-03-29T21:21:11Z
dc.date2012-03-29T21:21:11Z
dc.date2003
dc.date.accessioned2023-09-26T23:03:56Z
dc.date.available2023-09-26T23:03:56Z
dc.identifierGADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/3829
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8886439
dc.descriptionWe analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B. In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectHuman Immunodeficiency Virus
dc.subjectMolecular Epidemiology
dc.subjectDNA Viral
dc.subjectGenes Env
dc.subjectGenes Gag
dc.subjectInfecções por HIV
dc.subjectHIV-1
dc.subjectAdolescente
dc.subjectVariação Genética
dc.subjectHumanos
dc.subjectPrevalência
dc.subjectMeia-Idade
dc.titleMolecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
dc.typeArticle


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