Article
Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region
Registro en:
MORAES, Marcia Terezinha Baroni de et al. Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region. Pathogens, v. 10, n. 965, 10 p, July 2021.
2076-0817
10.3390/pathogens10080965
Autor
Moraes, Marcia Terezinha Baroni de
Leitão, Gabriel Azevedo Alves
Olivares, Alberto Ignácio Olivares
Xavier, Maria da Penha Trindade Pinheiro
Bispo, Romanul de Souza
Sharma, Sumit
Leite, José Paulo Gagliardi
Svensson, Lennart
Nordgren, Johan
Resumen
Sapovirus is an important etiological agent of acute gastroenteritis (AGE), mainly in
children under 5 years old living in lower-income communities. Eighteen identified sapovirus
genotypes have been observed to infect humans. The aim of this study was to identify sapovirus
genotypes circulating in the Amazon region. Twenty-eight samples were successfully genotyped
using partial sequencing of the capsid gene. The genotypes identified were GI.1 (n = 3), GI.2 (n = 7),
GII.1 (n = 1), GII.2 (n = 1), GII.3 (n = 5), GII.5 (n = 1), and GIV.1 (n = 10). The GIV genotype was the
most detected genotype (35.7%, 10/28). The phylogenetic analysis identified sapovirus genotypes
that had no similarity with other strains reported from Brazil, indicating that these genotypes may
have entered the Amazon region via intense tourism in the Amazon rainforest. No association
between histo-blood group antigen expression and sapovirus infection was observed.