Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region

dc.creatorMoraes, Marcia Terezinha Baroni de
dc.creatorLeitão, Gabriel Azevedo Alves
dc.creatorOlivares, Alberto Ignácio Olivares
dc.creatorXavier, Maria da Penha Trindade Pinheiro
dc.creatorBispo, Romanul de Souza
dc.creatorSharma, Sumit
dc.creatorLeite, José Paulo Gagliardi
dc.creatorSvensson, Lennart
dc.creatorNordgren, Johan
dc.date2021-10-06T10:08:20Z
dc.date2021-10-06T10:08:20Z
dc.date2021
dc.date.accessioned2023-09-26T20:55:03Z
dc.date.available2023-09-26T20:55:03Z
dc.identifierMORAES, Marcia Terezinha Baroni de et al. Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region. Pathogens, v. 10, n. 965, 10 p, July 2021.
dc.identifier2076-0817
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/49286
dc.identifier10.3390/pathogens10080965
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8866126
dc.descriptionSapovirus is an important etiological agent of acute gastroenteritis (AGE), mainly in children under 5 years old living in lower-income communities. Eighteen identified sapovirus genotypes have been observed to infect humans. The aim of this study was to identify sapovirus genotypes circulating in the Amazon region. Twenty-eight samples were successfully genotyped using partial sequencing of the capsid gene. The genotypes identified were GI.1 (n = 3), GI.2 (n = 7), GII.1 (n = 1), GII.2 (n = 1), GII.3 (n = 5), GII.5 (n = 1), and GIV.1 (n = 10). The GIV genotype was the most detected genotype (35.7%, 10/28). The phylogenetic analysis identified sapovirus genotypes that had no similarity with other strains reported from Brazil, indicating that these genotypes may have entered the Amazon region via intense tourism in the Amazon rainforest. No association between histo-blood group antigen expression and sapovirus infection was observed.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectSapovírus
dc.subjectAntígeno do grupo histo-sangue
dc.subjectRegião Amazônica
dc.subjectSapovirus
dc.subjectHisto-blood group antigen
dc.subjectAmazon region
dc.titleMolecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region
dc.typeArticle


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