artículo
Single-cell revolution unveils the mysteries of the regenerative mammalian digit tip
Fecha
2020Registro en:
10.1016/j.ydbio.2020.02.002
1095-564X
0012-1606
Autor
Riquelme Guzmán, Camilo
Contreras Saavedra, Osvaldo Isaías
Institución
Resumen
The digit tip is an exciting model for studying regeneration in mammals, but the precise mechanisms and the populations of cells involved in the formation and remodeling of the blastema remain unknown. In an exciting new work, Storer et al. take advantage of single-cell RNAseq combined with Pdgfra+ lineage-tracing to open the way into the enigmatic world of mammalian tissue regeneration.