Articulo
Computational studies of the metal-binding site of the wild-type and the H46R Mutant of the copper, zinc superoxide dismutase.
Journal Inorganic Chemistry
Autor
Mera-Adasme, R.
Mendizábal, F.
Gonzalez, M.
Miranda-Rojas, S.
Olea-Azar, C.
Sundhol, D.
Institución
Resumen
Impairment of the Zn(II)-binding site of the copper, zinc superoxide dismutase (CuZnSOD) protein is involved in a number of hypotheses and explanations for the still unknown toxic gain of function mutant varieties of CuZnSOD that are associated with famil FONDAP FONDAP