We consistently quantize a class of relativistic nonlocal field equations characterized by a nonlocal kinetic term in the Lagrangian. We solve the classical nonlocal equations of motion for a scalar field and evaluate the on-shell Hamiltonian. The quantization is realized by imposing Heisenberg’s equation, which leads to the commutator algebra obeyed by the Fourier components of the field. We show that the field operator carries, in general, a reducible representation of the Poincare group. We also consider the Gupta-Bleuler quantization of a nonlocal gauge theory and analyze the propagators and the physical modes of the gauge field.Facultad de Ciencias Exactas