Psychobiological studies showing the serotonin involvement in cognition-related behavioral performance

Abstract

Gray (1987a) proposed that the behavioral inhibition (BIS) and behavioral activation systems (BAS) be assessed in humans. The objective of the present study was to test the psychometric properties of the BIS/BAS scales and the SPSRQ, which are self-report measures developed from the reinforcement sensitivity theory (Pickering, Corr, y Gray, 1999), and which have not been tested in Latin-American samples. Factor analyses of the BIS/BAS items did not supported the 4-factor structure, but a 2-factor one. On the contrary, factor analyses of the SPSRQ items supported the 2-factor structure. The BIS/BAS scales had less internal consistency, and lower reliability coefficients, compared to the SPSRQ. The results from convergent and concurrent validities showed mixed findings for both measures. Overall, the results support the psychometric properties of the SPSRQ more than those of the BIS/BAS scales in this Mexican sample. " Copyright 2009.",,,,,,,,,"http://hdl.handle.net/20.500.12104/43960","http://www.scopus.com/inward/record.url?eid=2-s2.0-70449355056&partnerID=40&md5=560d2113c2f64646cb77cec1fdb44a33",,,,,,"2",,"Anales de Psicologia",,"358

367",,"25",,"Scopus

WOS",,,,,,"Activation; Adults; Behavioural; Factor analyses; Inhibition; Psychometrics",,,,,,"Psychometric evaluation of the behavioral activation and behavioral inhibition systems in Mexican adults [Evaluación psicométrica de los sistemas de activación e inhibición del comportamiento en adultos mexicanos]",,"Article" "45734","123456789/35008",,"González-Burgos, I., Lab. Psicobiología, Div. Neurociencias, I. M. S. S., Guadalajara, Mexico, Lab. Neurobiol. Cel., Depto. Biol. Cel. Mol., Universidad de Guadalajara, Guadalajara, Mexico; Feria-Velasco, A., Lab. Neurobiol. Cel., Depto. Biol. Cel. Mol., Universidad de Guadalajara, Guadalajara, Mexico",,"Gonzalez-Burgos, I.

Feria-Velasco, A.",,"2013",,"Serotonin most often acts as an inhibitory neurotransmitter which also modulates post-synaptic activity within other neurotransmitter systems. Serotonin is synthesized from the essential amino acid tryptophan in Raphe complex neurons which innervate extensive brain regions including the cerebral cortex, hippocampus, basal ganglia and cerebellum. Cognitive information is processed through synaptic connections with other regions of the brain, forming neural circuits as well as sub-serving systems that influence behavior. Previously investigations have concluded that serotonin has a modulatory role in neural systems, causing functional activity in the organization of various processes that relate to cognitive activity such as learning, memory, maintaining attention and behavioral switching. Serotonergic modulatory mechanisms include plastic changes at different biological organizational levels ranging from the molecular level, to adaptive behavior. Several psychopathological entities are associated with abnormal variations in brain serotonin levels. However, these involve other neurotransmitter systems such as dopamine, norepinephrine or acetylcholine. Therefore, an experimental study of the physiological interaction between serotonin and other neurotransmitter systems in normal and atypical cognitive abilities would be crucial for the improvement of therapeutic strategies applied to patients showing psychopathologies associated with dysfunctional serotonin neurotransmission. " 2013 by Nova Science Publishers, Inc. All rights reserved.