Article
Long-Term Effects of the keepin' it REAL Model Program in Mexico: Substance Use Trajectories of Guadalajara Middle School Students
Fecha
2008Autor
Ramos-Zuniga, R.
Gomez, P.U.
Navarro Ruiz, A.
Luquin De A, S.
García-Estrada, J.
Institución
Resumen
Objective: The Mongolian gerbil is one of the main animal species used for the study of global ischemia, due to its specific Circle of Willis. Because of their anatomic variations, a large number of animals is needed. On account of the specific vulnerability of the hippocampus, striatum and neocortex, it is possible to evaluate the severity of the ischemic damage through an analysis of locomotor activity. The tests support the sensitvity of the experimental sample and compensate the interanimal variability. Methods: The locomotor pattern of 30 male Mongolian gerbils was recorded before they were subjected to experimental bilateral carotid clippage for 15 minutes followed by reperfusion. A transparent 75 x 50 x 90 cm acrylic box was filmed in order to determine the total distance covered by the animals in five minutes, for three consecutive days. The locomotor activity of the animals was also examined in an open field at 24 hours and seven days after ischemia. Serum neurospecific enolase (NSE) was measured in the ischemic group and compared with that of an intact control group. Results: The recording for normal animals was uniformly similar (average 200 squares in periphery), in the first trial of 3 consecutive days (188 +/- 6.7 S.D.). After ischemia, the numbers increased to 388 (± 40 S.D.), indicating that they were sensitive to the ischemic episode. Seven days later they returned to basal values. Serum NSE was high in the ischemic group versus the intact control group (S = <0.001). Conclusions: Locomotor activity in an open field is a useful reference as a predictive test to determine the sensitivity of experimental animals to ischemia. It is also associated to the degree of cerebral damage in global ischemia-reperfusion, and this behavior is representative of the expression of selective ischemic injury. The determination of NSE is useful as an associated parameter of ischemic injury. " Georg Thieme Verlag KG Stuttgart.",,,,,,"10.1055/s-2007-1022531",,,"http://hdl.handle.net/20.500.12104/42584","http://www.scopus.com/inward/record.url?eid=2-s2.0-42549144090&partnerID=40&md5=d03eac2412d431c0fe8ec052ffe9352a http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=18401820",,,,,,"2",,"Minimally Invasive Neurosurgery",,"87 90",,"51",,"Scopus WOS MEDLINE",,,,"Index Medicus;Animals;Biological Markers;Brain/bs [Blood Supply];Brain/pa [Pathology];Brain/pp [Physiopathology];Brain Edema/di [Diagnosis];Brain Edema/pa [Pathology];Brain Edema/pp [Physiopathology];Brain Infarction/di [Diagnosis];Brain Infarction/pa [Pathology];Brain Infarction/pp [Physiopathology];Brain Ischemia/di [Diagnosis];Brain Ischemia/pa [Pathology];Brain Ischemia/pp [Physiopathology];Cerebrovascular Circulation/ph [Physiology];Disability Evaluation;Disease Models, Animal;Gerbillinae;Male;Motor Activity/ph [Physiology];Phosphopyruvate Hydratase/bl [Blood];Predictive Value of Tests;Reperfusion Injury/di [Diagnosis];Reperfusion Injury/pa [Pathology];Reperfusion Injury/pp [Physiopathology]",,"Cerebral ischemia; Hippocampus; Locomotor hyperactivity; Mongolian gerbil",,,,,,"Locomotor activity is a predictive test after global ischemia-reperfusion in Mongolian gerbils",,"Article"
"38316","123456789/35008",,,"Valdez Zepeda, Andrés",,"1999",,,,,,,,,,"0188-5405",,"http://hdl.handle.net/20.500.12104/36537",,"Español",,,,"105",,"Este país (México, D.F.)",,"38-40",,,,"CLASE",,,,,,,,"Proceso político",,"Las virtudes del marketing político: un ensayo en su defensa","Las virtudes del marketing político",,,"journalArticle",
"44364","123456789/35008",,"Ramírez-Herrejón, J.P., Centro de Investigaciones Biológicas del Noroeste, Instituto Politécnico Nacional, 195 Col. Playa Palo de Santa Rita, La Paz, Baja California Sur 23096, Mexico; Zambrano, L., Departamento de Zoología, Instituto de Biología, Universidad Nacional Autónoma de México Ciudad Universitaria, México, D.F. 04510, Mexico; Mercado-Silva, N., Departamento de Ecología y Recursos Naturales, Centro Universitario de la Costa Sur Universidad de Guadalajara, Autlán de la Grana, Jalisco, 48900, Mexico; Torres-Téllez, A., Laboratorio de Biología Acuática, Universidad Michoacana de San Nicolás de Hidalgo Morelia, Michoacán 58080, Mexico; Pineda-García, F., Escuela Nacional de Estudios Superiores, Unidad Morelia, Universidad Nacional Autónoma de México, Antigua Carretera a Pátzcuaro 8701, Morelia, Michoacán 58190, Mexico; Caraveo-Patiño, J., Centro de Investigaciones Biológicas del Noroeste, Instituto Politécnico Nacional, 195 Col. Playa Palo de Santa Rita, La Paz, Baja California Sur 23096, Mexico; Balart, E.F., Centro de Investigaciones Biológicas del Noroeste, Instituto Politécnico Nacional, 195 Col. Playa Palo de Santa Rita, La Paz, Baja California Sur 23096, Mexico",,"Ramirez-Herrejon, J.P. Zambrano, L. Mercado-Silva, N. Torres-Tellez, A. Pineda-García, F. Caraveo-Patino, J. Balart, E.F.",,"2014",,"Fish assemblages of lakes from central México have been altered as a result of water over-exploitation, pollution, habitat fragmentation, and introduction of exotic species. Patterns and the extent of change in most of these systems are poorly documented. This paper presents a long-term study of changes in the fish fauna of Lago de Pátzcuaro (State of Michoacán, México). Long-term information (years 1900-2010) of fish communities was used to explore trends in the composition of the fish community and their ecological attributes. Trends across time for each fish guild were evaluated through a multivariate analysis of variance. Native species dominated total species richness over the entire study period, but exotic fish comprised 46% of the community in the 2010s. During the last 110 years, there has been a decline in the number of carnivore species and an increase of omnivore species in the Lago de Pátzcuaro fish community. Sensitive species have disappeared from the lake and species tolerant to environmental degradation have increased from 13 to 61%. The data suggest that anthropic effects on the environmental condition of Lago de Pátzcuaro are associated with the loss of ecosystem elements (fish species) and ecosystem processes (species interactions). Ecological restoration and conservation programs must include information of these long term studies to be more effective in their efforts.",,,,,,"103856/vol42-issue1-fulltext-11",,,"http://hdl.handle.net/20.500.12104/42585","http://www.scopus.com/inward/record.url?eid=2-s2.0-84899654535&partnerID=40&md5=7e21e59d687ec7036309ae412e89d570",,,,,,"1",,"Latin American Journal of Aquatic Research",,"137 149",,"42",,"Scopus ScIELO WOS",,,,,,"Ecological guilds; Environmental degradation; Exotic species; Historical analysis; México; Shallow lake",,"lagos someros; degradación ambiental; gremios ecológicos; análisis históricos; especies exóticas; México",,,,"Long term changes in the fish fauna of Lago de pátzcuaro in central México [Cambios a largo plazo en la fauna de peces del lago de pátzcuaro en México central]",,"Article"
"38317","123456789/35008",,,,"Cortázar Rodríguez, Francisco Javier",,"2000",,,,,,,,,,"0188-252X","http://hdl.handle.net/20.500.12104/36538",,,"Español",,,,"38",,"Comunicación y sociedad",,"251-256",,,,"CLASE",,,,,,,,"Tecnología",,,"Le culte de l'Internet. Une menace pour le lien social?","Le culte de l'Internet. Une menace pour le lien social?, Philippe Breton, París, La Decouverte, 2000, 125 páginas",,"journalArticle"
"44365","123456789/35008",,"Valencia, R.R., Pediatic Dentistry and Orthodontics, Universidad Tecnológica de México, Mexico; Espinosa, R.R., Department of Oral Rehabilitation, Health Science and Environmental Centre, Universidad de Guadalajara, Mexico; Torres, M.M., Department of Oral Pathology and Genetics, Universidad Nacional Autónoma de México, Mexico; Saadia, M.M.",,"Valencia, R.R. Espinosa, R.R. Torres, M.M. Saadia, M.M.",,"2009",,"The aim of this study was to analyze the pulp behavior 17 hemisectioned primary second mandibular molars, exposed into the oral environment. The mesial crown and root portions were extracted after 8 months and analyzed histologically. Results: The cardinal signs such as pain, sensitivity and necrosis were not found in any of these teeth with the exception of one case which had a previous restoration. The formation of pulp polyps, pulp calcifications and pulp obliteration were seen as a normal physio-pathological response. Conclusions: Exposed pulps, reacted forming pulp polyps and in a similar fashion to exfoliating primary teeth but in an accelerated manner.",,,,,,,,,"http://hdl.handle.net/20.500.12104/42586","http://www.scopus.com/inward/record.url?eid=2-s2.0-70450267591&partnerID=40&md5=89e87093f277b073e5035732f0592ab7",,,,,,"1",,"Journal of Clinical Pediatric Dentistry",,"19 24",,"34",,"Scopus WOS",,,,,,"Dental pulp; Hemisection; Physiology; Primary teeth; Pulp calcification; Pulp polyps; Pulp stones",,,,,,"Long term histological response of hemisectioned exposed primary pulps. An in vivo study",,"Article"
"38318","123456789/35008",,"Peredo Merlo, María Alicia Universidad de Guadalajara",,"Peredo Merlo, María Alicia Universidad de Guadalajara",,"2005",,,,,,,,,,"1665-0565","http://hdl.handle.net/20.500.12104/36539",,,"Español",,,,"33",,"Espiral. Estudios sobre estado y sociedad",,"167-188",,"11",,"CLASE",,,,"Evaluación educativa",,,,,,,"¿Es verdad que México busca formar lectores?","¿Es verdad que México busca formar lectores?",,"journalArticle"
"44366","123456789/35008",,"Salazar-Páramo, M., Clinical Epidemiology Research Unit, Hospital de Especialidades, Universidad de Guadalajara, Guadalajara, Mexico; Jara, L.J., Department of Rheumatology, Hospital de Especialidades, Instituto Mexicano del Seguro Social, Mexico City, Mexico; Ramos, A., Department of Rheumatology, Hospital de Especialidades, Instituto Mexicano del Seguro Social, Mexico City, Mexico; Barile, L., Department of Rheumatology, Hospital de Especialidades, Instituto Mexicano del Seguro Social, Mexico City, Mexico; Machado, G., Justo Sierra 2821, Col. Vallarta Norte, Guadalajara, Jal. C.P. 44690, Mexico; García-De La Torre, I., Department of Immunology and Rheumatology, Hospital General de Occidente de la Secretaría de Salud, Universidad de Guadalajara, Guadalajara, Mexico",,"Salazar-Paramo, M. Jara, L.J. Ramos, A. Barile, L. Machado, G. García-De La Torre, I.",,"2002",,"The objective of this study was to perform a longitudinal follow-up of antinuclear antibodies (ANAs) and anticardiolipin antibodies titers (aCL) throughout pregnancy in a group of patients with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) patients during their therapy for the prevention of fetal loss and to examine their relationship with pregnancy outcome. Thirty patients and 15 controls were followed in the study. Fifteen patients had SLE (group I) and 15 had APS (group II, of which seven patients had primary APS and eight had APS secondary to SLE). All patients were receiving therapy for the prevention of fetal loss with prednisone and aspirin as part of an ongoing clinical trial in lupus pregnancy. If there was a history of previous thrombosis, heparin was added. Blood samples were taken at the 1st, 2nd, and 3rd trimesters (T) of pregnancy in order to assess the presence of IgG and IgM aCL antibodies (ELISA), anti-dsDNA (C. luciliae) ANAs (HEp-2 cells), and immunospecific antibodies (antiextractable nuclear antigens). We collected 90 samples from patients and 45 samples from healthy controls. Group I (SLE) ANAs were positive in 100% during the 1st T, 67% in the 2nd T, and 67% in the 3rd T, with various immunofluorescence patterns. In five patients, aCL antibodies were detected without a history of APS (one in 1st T, three in 2nd T, and one in 3rd T). Fetal loss was observed in two patients, in one of whom it was associated with nephritis, high titers of ANAs, and anti-dsDNA. Another patient had pulmonary hemorrhage with anti-dsDNA and aCL. In group II, all but one patient with primary APS were negative to ANAs. In secondary APS, by contrast, 6/8 patients (75%) had positive ANAs at least during the 1st T. All seven patients with primary APS and 6/8 with secondary APS had aCL during pregnancy. In 9/15 (60%) patients from the APS group with a history of previous fetal loss, aCL became negative during pregnancy and they had live births. The disappearance of aCL was associated with improved fetal survival (relative risk, or RR, 0.67). ANAs in the control group were positive in 7% at low titers, and all of them were negative for aCL. Despite treatment, ANAs are prevalent during pregnancy in SLE patients and APS secondary to SLE. During pregnancy in SLE, aCL titers may appear. Decreasing titers and/or disappearance of aCL correlated with improved fetal prognosis in a subset of patients with APS.",,,,,,"10.1007/s00296-002-0207-x",,,"http://hdl.handle.net/20.500.12104/42587","http://www.scopus.com/inward/record.url?eid=2-s2.0-0036036485&partnerID=40&md5=54d088c5db27fbdc0df3a65d204ef2ad http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12172952",,,,,,"4",,"Rheumatology International",,"142 147",,"22",,"Scopus WOS MEDLINE",,,,"Index Medicus;Adult;Antibodies, Anticardiolipin/an [Analysis];Antibodies, Antinuclear/an [Analysis];Antiphospholipid Syndrome/di [Diagnosis];Antiphospholipid Syndrome/dt [Drug Therapy];Antiphospholipid Syndrome/im [Immunology];Biological Markers/an [Analysis];Case-Control Studies;Enzyme-Linked Immunosorbent Assay;Female;Humans;Longitudinal Studies;Lupus Erythematosus, Systemic/di [Diagnosis];Lupus Erythematosus, Systemic/dt [Drug Therapy];Lupus Erythematosus, Systemic/im [Immunology];Prednisone/ad [Administration & Dosage];Pregnancy;Pregnancy Complications/dt [Drug Therapy];Pregnancy Complications/im [Immunology];Pregnancy Outcome;Probability;Prognosis;Reference Values;Sensitivity and Specificity;Severity of Illness Index",,"Antinuclear antibodies; Antiphospholipid syndrome; Pregnancy in SLE",,,,,,"Longitudinal study of antinuclear and anticardiolipin antibodies in pregnant women with systemic lupus erythematosus and antiphospholipid syndrome",,"Article"
"38319","123456789/35008",,,,"Moreno Pérez, Ana Rosa",,"2003",,,,,,,,,,"0187-7674","http://hdl.handle.net/20.500.12104/36540",,,"Español",,,,"83",,"Confines de relaciones internacionales y ciencia política",,"V-VII",,"15",,"CLASE",,,,,,,,"Economía industrial",,,,"Lechuga Montenegro, Jesús. El cambio estructural en la industria manufacturera de Jalisco. Hacia un nuevo patrón de especialización, Universidad Autónoma Metropolitana-Azcapotzalco/Universidad de Guadalajara",,"journalArticle"
"44367","123456789/35008",,"Marsiglia, F.F., School of Social Work, Arizona State UniversityPhoenix, AZ, United States; Kulis, S.S., T. Denny Sanford School of Social and Family Dynamics, Arizona State UniversityTempe, AZ, United States; Booth, J.M., Southwest Interdisciplinary Research Center, Arizona State UniversityPhoenix, AZ, United States; Nuño-Gutierrez, B.L., Mexican Social Security Institute, University of GuadalajaraGuadalajara, Mexico; Robbins, D.E., Southwest Interdisciplinary Research Center, Arizona State UniversityPhoenix, AZ, United States",,"Marsiglia, F.F. Kulis, S.S. Booth, J.M. Nuno-Gutierrez, B.L. Robbins, D.E.",,"2015",,"In the face of rising rates of substance use among Mexican youth and rapidly narrowing gender differences in use, substance use prevention is an increasingly urgent priority for Mexico. Prevention interventions have been implemented in Mexico but few have been rigorously evaluated for effectiveness. This article presents the long term effects of a Mexico-based pilot study to test the feasibility of a linguistically specific (Mexican Spanish) adapted version of keepin´it REAL, a school-based substance abuse prevention model program. University affiliated researchers from Mexico and the US collaborated on the study design, program implementation, data collection, and analysis. Students and their teachers from two middle schools (secundarias) in Guadalajara participated in this field trial of Mantente REAL (translated to Spanish). The schools were randomly assigned to treatment and control conditions. The sample of 431 students reported last 30 day substance use at three times (one pretest and two posttests). Changes in substance use behaviors over time were examined using growth curve models. Long term desired intervention effects were found for alcohol and marijuana use but not for cigarettes. The intervention effects were greater for girls than for boys in slowing the typical developmental increase over time in alcohol use. Marijuana effects were based on small numbers of users and indicate a need for larger scale studies. These findings suggest that keepin'it REAL is a promising foundation for cultural program adaptation efforts to create efficacious school-based universal prevention interventions for middle school students in Mexico. " 2014, Springer Science+Business Media New York.