Article
Synbiotic therapy decreases microbial translocation and inflammation and improves immunological status in HIV-infected patients: A double-blind randomized controlled pilot trial
Fecha
2007Registro en:
10.1186/1475-2891-11-90
Autor
Ortiz-Ibarra, H.
Casillas, N.
Soto, V.
Barcena-Soto, M.
Torres-Vitela, R.
de la Cruz, W.
Gomez-Salazar, S.
Institución
Resumen
The use of an electrochemical reactor operated under different flow conditions to deposit silver from aqueous AgNO3 solutions and tartaric acid as an organic additive on a commercial activated carbon with ultimate bactericidal applications in water purification processes is presented. The characterization of carbon/silver samples was studied by BET, FTIR, X-ray diffraction, XPS, and SEM techniques. The bactericidal activity of the carbon/silver samples was tested on drinking water samples inoculated with E. coli. A reduction of carbon surface area was detected and was caused by increased amounts of silver deposited on carbon samples. Adherent silver deposits were obtained on the carbon/silver samples. X-ray diffraction studies of carbon with electrodeposited silver showed two different preferential deposition planes, [111] and [220]. The FTIR results confirm the presence of carboxyl, phenolic, quinone, and ether surface groups. The XPS results suggest the formation of Ag2O and AgO surface species and confirm the reduction of silver to the metallic form. Antimicrobial activity toward E. coli indicated reductions by up to 7 orders of magnitude in the log CFU/mL in just 10 min contact time and for silver contents of 2.47 wt%. " 2007 Elsevier Inc. All rights reserved.",,,,,,"10.1016/j.jcis.2007.05.062",,,"http://hdl.handle.net/20.500.12104/44855","http://www.scopus.com/inward/record.url?eid=2-s2.0-34548059120&partnerID=40&md5=c8ec2dd932fef50529b49300f1bba6cb",,,,,,"2",,"Journal of Colloid and Interface Science",,"562 571",,"314",,"Scopus WOS",,,,,,"Activated carbon; Bactericide; Silver; XPS",,,,,,"Surface characterization of electrodeposited silver on activated carbon for bactericidal purposes",,"Article"
"46646","123456789/35008",,"Guerrerosantos, J., Reconstructive Plastic Surgery, University of Guadalajara Medical College, 44680 Guadalajara, Jalisco, Mexico",,"Guerrerosantos, J.",,"1987",,"The purpose of this paper is to report a modification of the commonly used incisions for obtaining a compositve earlobe graft. A procedure is described to reconstruct a skin fold between the earlobe and the cheek after excision of the graft. The presence of a definitive skin fold, the avoidance of scar and notching in the lobule border, and the maintenance of a normal lobule contour under a reconstructed earlobe after the excision of a composite graft do much to enhance its appearance. Two demonstrative patients are illustrate.",,,,,,,,,"http://hdl.handle.net/20.500.12104/44867","http://www.scopus.com/inward/record.url?eid=2-s2.0-0023640561&partnerID=40&md5=8056f5737de5ac30b8a2622343cb0adc",,,,,,"1",,"Plastic and Reconstructive Surgery",,"125 128",,"80",,"Scopus WOS",,,,,,,,,,,,"Surgical scar camouflage in donor site for composite earlobe graft",,"Article"
"46677","123456789/35008",,"González-Hernández, L.A., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico; Jave-Suarez, L.F., Centro de Investigación Biomédicas de Occidente (CIBO), Instituto Mexicano Del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico; Fafutis-Morris, M., Centro Universitario de Ciencias de la Salud (CUCS), UdeG, Guadalajara, Jalisco, Mexico; Montes-Salcedo, K.E., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico; Valle-Gutierrez, L.G., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico; Campos-Loza, A.E., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico; Enciso-Gómez, L.F., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico; Andrade-Villanueva, J.F., HIV Unit Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara, Calle Hospital 278, Colonia Alcalde Barranquitas, Guadalajara, Jalisco, 44280, Mexico",,"Gonzalez-Hernandez, L.A. Jave-Suarez, L.F. Fafutis-Morris, M. Montes-Salcedo, K.E. Valle-Gutierrez, L.G. Campos-Loza, A.E. Enciso-Gomez, L.F. Andrade-Villanueva, J.F.",,"2012",,"Background: HIV-infection results in damage and dysfunction of the gastrointestinal system. HIV enteropathy includes pronounced CD4+ T-cell loss, increased intestinal permeability, and microbial translocation that promotes systemic immune activation, which is implicated in disease progression. A synbiotic is the combination of probiotics and prebiotics that could improve gut barrier function. Our study goal was to determine whether the use of a synbiotic, probiotics or a prebiotic can recover immunological parameters in HIV-infected subjects through of a reduction of microbial translocation and pro-inflammatory cytokine production. Methods. A randomized, double-blind controlled study was performed; twenty Antiretroviral treatment-naive HIV-infected subjects were subgrouped and assigned to receive a synbiotic, probiotics, a prebiotic, or a placebo throughout 16weeks. Results: We had no reports of serious adverse-events. From baseline to week 16, the synbiotic group showed a reduction in bacterial DNA concentrations in plasma (p=0.048). Moreover, the probiotic and synbiotic groups demonstrated a decrease in total bacterial load in feces (p=0.05). The probiotic group exhibited a significant increment of beneficial bacteria load (such as Bifidobacterium; p=0.05) and a decrease in harmful bacteria load (such as Clostridium; p=0.063). In the synbiotic group, the CD4+ T-cells count increased (median: +102 cells/?L; p=0.05) and the level of Interleukin 6 cytokine decreased significantly (p=0.016). Conclusions: Our study showed a significant increase in CD4+ T lymphocyte levels in the synbiotic group, which could delay the initiation of antiretroviral therapy and decrease costs in countries with limited resources. " 2012 González-Hernández et al.; licensee BioMed Central Ltd.