The consequences of fatal and non-fatal road traffic injuries (RTI) at the personal and household levels were analysed using qualitative interviews of 12 injured and of 12 relatives of people who died for this reason. Collisions change physical and mental health both of the injured and of their relatives. This leads to changes in daily activities and even to the redefinition of future life. RTI also changes the way people see and act in life, becoming an experience that teaches them. Survivors commonly transmit a road safety message afterwards. Changes in family life were evident (in extreme cases family's composition also changed), affecting intra-familial relationships. Associated unexpected and unplanned expenditures and loss of income have consequences in the short, medium and long term that unbalance household's economies and immerse people into a constant stress. Individuals and family's future plans are occasionally condition to whether they have or not debts. Household dependence in economic terms was sometimes observed, as well as uncertainty about future life and household's sustainability. Sometimes, households change and adapt their life to what they now are able to afford, having important repercussions in vital spheres. " 2012 Copyright Taylor and Francis Group, LLC.",,,,,,"10.1080/17457300.2011.603155",,,,"http://www.scopus.com/inward/record.url?eid=2-s2.0-84859480362&partnerID=40&md5=2cd1dc8f74f87d90d6edf490e18f20e3http://hdl.handle.net/20.500.12104/39099",,,,,,"1",,"International Journal of Injury Control and Safety Promotion",,"6979",,"19",,"ScopusWOS",,,,,,"intangible cost; qualitative approach; road traffic injuries",,,,"A qualitative approach to the intangible cost of road traffic injuries",,,,"Article", "40886","123456789/35008",,"Corona Nakamura, A., CUCEI, Universidad de Guadalajara, Revolution 1500, Guadalajara, Jalisco, Mexico; Ruelas, R., CUCEI, Universidad de Guadalajara, Revolution 1500, Guadalajara, Jalisco, Mexico; Andina, D., Depto. SSR, Universidad Politécnica de Madrid, E.T.S. Ingenieros de Telecomunicación, Madrid, Spain; Ojeda-Magaña, B., Depto. SSR, Universidad Politécnica de Madrid, E.T.S. Ingenieros de Telecomunicación, Madrid, Spain",,"Corona Nakamura, A.Ruelas, R.Andina, D.Ojeda-Magana, B.",,"2005",,"This article presents an analysis of the application of the neuro-fuzzy models in the medical area. We have chosen this field since it has suitable conditions to obtain efficient models. The general characteristics of the models are analyzed as well as those used in this field. This work concludes how these models can be applied in order to obtain better results particularly in the domain of application considered.",,,,,,,,,"http://hdl.handle.net/20.500.12104/39107","http://www.scopus.com/inward/record.url?eid=2-s2.0-84867413280&partnerID=40&md5=35569c589585228b8fef2e7c28d4b129",,,,,,,,"WMSCI 2005 - The 9th World Multi-Conference on Systemics, Cybernetics and Informatics, Proceedings",,"344349",,"1",,"Scopus",,,,,,"Fuzzy system; Medicine; Neural network; Neuro-fuzzy",,,,,,"A review of benefits of neuro-fuzzy systems applied in medicine",,"Conference Paper" "40873","123456789/35008",,,"Verduzco Chávez, B.",,"1997",,,,,,,,,,"0187-7674",,"http://hdl.handle.net/20.500.12104/39094",,"Español",,,,"56",,"Confines de relaciones internacionales y ciencia política",,"42219",,"10",,"CLASE",,,,,,,,"Sociología urbana",,"Criterios económicos y políticos de renovación urbana en Plaza tapatia",,,,"journalArticle", "44692","123456789/35008",,"Nava, M.P., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico; Trejo, J.M., Hospital de Pediatría, CMN Siglo XXI, Guadalajara, Mexico; Aguilar-Luna, C., Hospital de Pediatría, CMNO, IMSS, Guadalajara, Mexico; Barros-Núñez, P., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico; de la Luz Chávez, Ma., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico; Magaña, M.T., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico; Perea, J., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico; Ibarra, B., División de Genética, Centro de Investigación Biomédica de Occidente, CMNO, Sierra Mojada No. 800, 44340 Guadalajara Jal., Mexico, Universidad de Guadalajara, Guadalajara, Mexico",,"Nava, M.P.Trejo, J.M.Aguilar-Luna, C.Barros-Nunez, P.de la Luz Chavez Ma.Magana, M.T.Perea, J.Ibarra, B.",,"2006",,"?-Thalassemia is one of the most prevalent hemoglobin disorders in the world, in South-East Asians, the - _SEA allele is widely found in the HbH disease patients. The purpose of this work is to describe the molecular characteristics of Hemoglobin H disease in three patients from two Mexican families, as well to analyze the DNA sequence of the - _SEA allele to determine the precise site of the crossover. The -?3.7 and - _SEA alleles were identified using an established long-PCR method modified in our laboratory. The crossover site of - _SEA mutation was analyzed by DNA sequencing. The three HbH subjects showed the same genotype -?3.7/- _SEA. The -? 3.7 allele has been observed in almost every racial studied group, whereas the - _SEA allele is predominant in South-East Asian countries. DNA analysis through the breakpoint sites of the - _SEA allele in both families showed the 5? breakpoint at the third base of codon 28 in the ??2 gene and the 3? breakpoint within an Alu-Jo sequence, 1,328 nucleotides upstream of the 3'HVR. Therefore the size of the deletion is 19,303 nucleotides. This is the first report in which the flanking deletion sites of the - _SEA mutation have been analyzed in Mexican patients, the 5? and 3? ends of the deletion is well determined.",,,,,,,,,"http://hdl.handle.net/20.500.12104/42913","http://www.scopus.com/inward/record.url?eid=2-s2.0-33847173392&partnerID=40&md5=ced3202b50a3016685842168747dc4b9",,,,,,"4",,"Revista de Investigacion Clinica",,"313317",,"58",,"ScopusWOS",,,,,,"?-Thalassemia; -?3.7 deletion; -SEA deletion; Hemoglobin H disease",,,,,,"Molecular characterization of the - SEA alpha thalassemia allele in Mexican patients with HbH disease",,"Article" "40896","123456789/35008",,"Cisneros-Mejorado, A., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, México.; Sánchez, D.",,"Cisneros-Mejorado, A.Sanchez, D.",,"2011",,"In their transit through the female genital tract, mammalian sperm acquire the ability to fertilize the egg in a process called capacitation. During this event the intracellular levels of cAMP and cGMP increase, suggesting that cyclic nucleotide-gated (CNG) channels, which have been identified in mammalian sperm, play a functional role in their physiology. Here we report an electrophysiological characterization of the effect of cyclic nucleotides on mouse sperm. Using the patch-clamp technique in the whole-cell configuration, we show that macroscopic ionic currents are augmented by the addition of both, 8Br-cAMP and 8Br-cGMP to non-capacitated mouse sperm. Although cyclic nucleotide regulates the activity of CNG channels, disparate effects of cyclic nucleotides may also occur. Addition of L-cis-diltiazem (50 microM), a specific inhibitor of CNG channels, partially blocked currents elicited by cGMP, suggesting that CNG channels play a role in the fertilization capability of mammalian sperm.",,,,,,,,,"http://hdl.handle.net/20.500.12104/39117","http://www.scopus.com/inward/record.url?eid=2-s2.0-84859727797&partnerID=40&md5=8deab9c82d678927845b1b689d3e582fhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22423576",,,,,,,,"Proceedings of the Western Pharmacology Society",,"2729",,"54",,"ScopusMEDLINE",,,,"Index Medicus;8-Bromo Cyclic Adenosine Monophosphate/pd [Pharmacology];Animals;Cyclic GMP/aa [Analogs & Derivatives];Cyclic GMP/pd [Pharmacology];Cyclic Nucleotide-Gated Cation Channels/ph [Physiology];Male;Mice;Sperm Capacitation/ph [Physiology]",,,,,,,,"A role for cyclic nucleotide-gated channels in the capacitation of mammalian sperm.",,"Article" "44693","123456789/35008",,"Gómez-Hernández, C., Departamento de Clínica Médica, Universidade Federal do Triángulo Mineiro, Uberaba, MG, Brazil; Rezende-Oliveira, K., Campus do Pontal, Universidade Federal de Uberlândia, Ituiutaba, MG, Brazil; Nascentes, G.A.N., Instituto Federal do Triángulo Mineiro, Uberaba, MG, Brazil; Batista, L.R., Departamento de Clínica Médica, Universidade Federal do Triángulo Mineiro, Uberaba, MG, Brazil; Kappel, H.B., Departamento de Clínica Médica, Universidade Federal do Triángulo Mineiro, Uberaba, MG, Brazil; Martinez-Ibarra, J.A., Departamento de Entomologia Médica, Universidad de Guadalajara, Centro Universityrio del Sur, Ciudad Guzman, JAL, Mexico; Contreras, F.T., Departamento de Parasitologia, Universidad de Guadalajara, Centro Univerisitario de los Altos, Tepatitlán, JAL, Mexico; Lages-Silva, E., Laboratorio de Parasitologia, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triángulo Mineiro, Uberaba, MG, Brazil; Ramírez, L.E., Laboratorio de Parasitologia, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triángulo Mineiro, Uberaba, MG, Brazil",,"Gomez-Hernandez, C.Rezende-Oliveira, K.Nascentes, G.A.N.Batista, L.R.Kappel, H.B.Martinez-Ibarra, J.A.Contreras, F.T.Lages-Silva, E.Ramirez, L.E.",,"2011",,"Introduction: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological characterization, and the paucity of information on the clinical and biological aspects of Chagas disease in Mexico, this study aimed to identify the molecular and biological characterization of Trypanosoma cruzi isolates from different endemic areas of this country, especially of the State of Jalisco. Methods: Eight Mexican Trypanosoma cruzi strains were biologically and genetically characterized (PCR specific for Trypanosoma cruzi, multiplex-PCR, amplification of space no transcript of the genes of the mini-exon, amplification of polymorphic regions of the mini-exon, classification by amplification of intergenic regions of the spliced leader genes, RAPD - (random amplified polymorphic DNA). Results: Two profiles of parasitaemia were observed, patent (peak parasitaemia of 4.6 10 6 to 10 7 parasites/mL) and subpatent. In addition, all isolates were able to infect 100% of the animals. The isolates mainly displayed tropism for striated (cardiac and skeletal) muscle. PCR amplification of the mini-exon gene classified the eight strains as TcI. The RAPD technique revealed intraspecies variation among isolates, distinguishing strains isolated from humans and triatomines and according to geographic origin. Conclusions: The Mexican T. cruzi strains are myotrophic and belong to group TcI.",,,,,,"10.1590/S0037-86822011005000058",,,"http://hdl.handle.net/20.500.12104/42914","http://www.scopus.com/inward/record.url?eid=2-s2.0-84855846824&partnerID=40&md5=adbeb0389d881cacabcbda46e1a2bd49",,,,,,"6",,"Revista da Sociedade Brasileira de Medicina Tropical",,"684690",,"44",,"ScopusWOS",,,,,,"Biological characterization; Genetic characterization; Mexico; Trypanosoma cruzi",,,,,,"Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model [Caracterização molecular de cepas mexicanas de Trypanosoma cruzi e seu comportamento no modelo experimental do camundongo]",,"Article" "40874","123456789/35008",,"Leboeuf-Pasquier, J., DIP, CUCEI, University of Guadalajara, Mexico; Gómez Ávila, G.F., DIP, CUCEI, University of Guadalajara, Mexico; González Pacheco Oceguera, J.E., DIP, CUCEI, University of Guadalajara, Mexico",,"Leboeuf-Pasquier, J.Gomez Avila, G.F.Gonzalez Pacheco Oceguera, J.E.",,"2013",,"In the present paper, a learning based controller that performs as an auditory subsystem is described. Based on the Growing Functional Modules (GFM) paradigm, the auditory subsystem is the result of the interconnection of four kinds of components: Global Goals, Acting Modules, Sensations and Sensing Modules. The resulting controller is radically different from conventional speech recognition due to its ability to gradually learn in context a set of vocal commands while performing in a virtual environment. Recognition is considered as satisfactory when the robot's behavior is in accordance with the commands' meaning. This learning process may be compared to how a dog learns to obey its master's orders. The experiment described in this paper illustrates the design process of a GFM controller. It exhibits the behavior of the control process and principally, exposes the inherent philosophy of the GFM approach. " 2013 Springer-Verlag.