Universidad San Sebastián (Chile): últimos ingresos
Mostrando ítems 981-1000 de 2845
-
Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegeneration
(2021-05-05)Alteration to endoplasmic reticulum (ER) proteostasis is observed in a variety of neurodegenerative diseases associated with abnormal protein aggregation. Activation of the unfolded protein response (UPR) enables an adaptive ... -
Somatotipo, estado nutricional y nivel de glucemia de estudiantes de educación física
(2015-08-28)Introduction: classical studies have compared the glycemia with the nutritional status in both children and adults; however studies that consider also somatotype are unknown. Objective: associating the somatotype and ... -
Hydroxyapatite nanocrystals synthesized from calcium rich bio-wastes
(2018-11-01)Hydroxyapatite nanocrystals were synthesized by wet chemical precipitation using bio-waste shells of mollusk (clam and mussel) and egg as feedstock materials. The powdered shells were calcined, dissolved in water, and the ... -
Cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells
(2023-02)Glioblastoma (GBM) is the most common and aggressive type of brain tumor due to its elevated recurrence following treatments. This is mainly mediated by a subpopulation of cells with stemness traits termed glioblastoma ... -
Higher-Spin Symmetries and Deformed Schrödinger Algebra in Conformal Mechanics
(2018)The dynamical symmetries of 1+1-dimensional Matrix Partial Differential Equations with a Calogero potential (with/without the presence of an extra oscillatorial de Alfaro-Fubini-Furlan, DFF, term) are investigated. The ... -
Flavoprotein-mediated tellurite reduction : Structural basis and applications to the synthesis of tellurium-containing nanostructures
(2016-07-26)The tellurium oxyanion tellurite (TeO32-) is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(P)H-dependent, reduction ... -
Rol de la microbiota intestinal en el desarrollo del hígado graso no alcohólico
(2021-04)Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of hepatic pathologies ranging from simple steatosis (SS) to hepatocellular carcinoma. Intestinal microbiota (IM) is composed of trillions of microorganisms ... -
The total mRNA concentration buffering system in yeast is global rather than gene-specific
(2021-10)Gene expression in eukaryotes does not follow a linear process from transcription to translation and mRNA degradation. Instead it follows a circular process in which cytoplasmic mRNA decay crosstalks with nuclear transcription. ... -
Correction to : Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure (Biological Research, (2021), 54, 1, (43), 10.1186/s40659-021-00365-z)
(2022-12)Following publication of the original article [1], the Figs. 2, 3 and 4 are misplaced. The correct order of figures is given in this erratum (Figs. 1, 2, 3, 4, 5, 6). The original article has been corrected. -
P2x7 receptor at the crossroads of t cell fate
(2020-07-02)The P2X7 receptor is a ligand-gated, cation-selective channel whose main physiological ligand is ATP. P2X7 receptor activation may also be triggered by ARTC2.2-dependent ADP ribosylation in the presence of extracellular ... -
Effect of dilution rate and methanol-glycerol mixed feeding on heterologous Rhizopus oryzae lipase production with Pichia pastoris Mut+ phenotype in continuous culture
(2015-05-01)The induction using substrate mixtures is an operational strategy for improving the productivity of heterologous protein production with Pichia pastoris. Glycerol as a cosubstrate allows for growth at a higher specific ... -
Occurrence and air-water diffusive exchange legacy persistent organic pollutants in an oligotrophic north Patagonian lake
(2022-03)In this study, the occurrence and diffusive air-water exchange of POPs in Panguipulli Lake (39°42′S-72°13′W), an oligotrophic lake located in northern Patagonia (Chile), were determined. Air and water samples were collected ... -
In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities : 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies
(2023)Glycogen synthase kinase 3 (GSK-3) is involved in different diseases, such as manic-depressive illness, Alzheimer’s disease and cancer. Studies have shown that insulin inhibits GSK-3 to keep glycogen synthase active. ... -
Astrocytic contribution to glutamate-related central respiratory chemoreception in vertebrates
(2021-12)Central respiratory chemoreceptors play a key role in the respiratory homeostasis by sensing CO2 and H+ in brain and activating the respiratory neural network. This ability of specific brain regions to respond to acidosis ... -
DNA methylation changes in genes coding for leptin and insulin receptors during metabolic-altered pregnancies : DNA methylation in LEPR and INSR
(2020-02-01)The overwhelming rates of obesity worldwide are a major concern due to the elevated medical costs associated and the poor quality of life of obese patients. In the recent years, it has become evident that the intrauterine ... -
Mindchords : A way to identify people's brains functional dynamics through a musical representation of the EEG
(2022)In this paper we report the use of a transformation of an EEG signal to a MIDI music representation. The subsequent analysis of the melodic and harmonic structure of this musical representation generated from the EEG, ... -
Astrocytes and endoplasmic reticulum stress : A bridge between obesity and neurodegenerative diseases
(2017-11)Endoplasmic reticulum (ER) is a subcellular organelle involved in protein folding and processing. ER stress constitutes a cellular process characterized by accumulation of misfolded proteins, impaired lipid metabolism and ... -
Neumonía neumocócica bacteriémica en adultos en hospital regional de Chile
(2018-07)Background: Bacteremic pneumococcal pneumonia (BPP) is a preventable disease with high morbimortality. Aim: To evaluate clinical aspects and mortality on BPP patients admitted to a Chilean regional hospital. Patients and ... -
Sodium intake is associated with endothelial damage biomarkers and metabolic dysregulation
(2018-09-11)BACKGROUND Mounting evidence has associated high sodium (HS) intake with hypertension, cardiovascular disease, and stroke. We investigated whether HS intake modulates the parameters of endothelial damage, inflammation, and ...