Universidad San Sebastián (Chile): últimos ingresos
Mostrando ítems 421-440 de 2845
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Hermenéutica objetiva : el caso de Emilio Betti
(2020)En el presente trabajo defenderemos que, en su teoría de la interpretación, Emilio Betti toma como base una estructura ontológica de la comprensión humana que resulta inadecuada. En particular, justificaremos que, si bien ... -
De la constitución moral de la sociedad a la educación moral según Durkheim
(2009)The moral constitution of society and moral education are two subjects closely linked in Durkheim's writings. The sociologist from Alsace addresses suicide and other anomic actions from the point of view of a moralist, a ... -
The Decline of the Family as a Source of Social Capital in the EU: Some Indicators
(2009)This article shows how social policy in the European Union (EU) fails to give proper attention to the family as a factor in social development and cohesion. It begins with a conceptual overview of the family as social ... -
Social Capital: Foundations and Some Social Policies in the EU
(2012)With this paper we want to show which three pillars are fundamental that lie within the social capital: trust, cooperation and the principle of general reciprocity. Some significant data about Abortion in the EU-27 and in ... -
The EQF Model and Teacher's Competences
(2012)The ‘Bologna Declaration’ has highlighted the importance of skills in Higher Education as well as primary and secondary education. The purpose of this paper is to show the most relevant aspects of the EQF model, and the ... -
Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells : Are mucins involved in Sjögren's syndrome?
(2015-05-05)Objectives. A hallmark characteristic of SS patients is the ectopic presence of the mucins MUC5B and MUC7 in the extracellular matrix of salivary glands that have lost apical-basolateral acinar-cell polarity. This study ... -
Enhanced degradation of proteins of the basal lamina and stroma by matrix metalloproteinases from the salivary glands of Sjögren's syndrome patients : Correlation with reduced structural integrity of acini and ducts
(2003-09-01)Objective. To determine the effect of matrix metalloproteinase (MMP) activity from the labial salivary glands (LSGs) of Sjögren's syndrome (SS) patients on proteins of the extracellular matrix (ECM) that form the basal ... -
Oral dryness in Sjögren's syndrome patients. Not just a question of water
(2013-03)Sjögren's syndrome (SS) is a chronic autoimmune disease of undefined etiology. Patients with this syndrome suffer from severe alterations in both the quality and quantity of saliva and tears, due to impaired function of ... -
Severe alterations in expression and localisation of α6β4 integrin in salivary gland acini from patients with Sjögren syndrome
(2009-06)Objectives: In salivary glands from patients with Sjögren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina ... -
Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sögren's syndrome
(2006-11)Objective. To investigate remodeling of the basal lamina of labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) by analyzing the expression of specific components that participate in its assembly and ... -
Changes in Rab3D expression and distribution in the acini of Sjögren's syndrome patients are associated with loss of cell polarity and secretory dysfunction
(2011-10)Objective Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ... -
Increased acinar damage of salivary glands of patients with Sjögren's syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3/tissue inhibitor of metalloproteinases 1 and matrix metalloproteinase 9/tissue inhibitor of metalloproteinases 1 ratios
(2005-09)Objective. Previous findings in labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) suggest that increased activity and expression of matrix metalloproieinase 9 (MMP-9) and MMP-3 trigger the destruction ... -
Alterations in type i hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with sjögren's syndrome
(2011-04)Objective: Acinar cells in the salivary glands of patients with Sjögren's syndrome (SS) display severe alterations in anchorage to the basal lamina. Bioinformatics analysis of the BP230 gene sequence has revealed the ... -
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjögren's syndrome : Association with mononuclear cell infiltration
(2006-02)Objective: To study the expression of laminin and type IV collagen as biomarkers of the organisation of the basal lamina of acini and ducts in labial salivary glands from patients with Sjögren's syndrome, and to relate ... -
Oral manifestations and their treatment in Sjögren's syndrome
(2014-03)Sjögren's syndrome (SS) is a complex, chronic, systemic, autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands, leading to dryness of the oral and ocular mucosae. Several ... -
OSCE un diseño de prueba de habilitación de admisión a la clínica dental
(2015)The Objective Structured Clinical mode of Examination (OSCE) has many attributes that recommend its adoption for assessment of certain elements of competence (communication skills assessment or data interpretation) and ... -
MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjögren's syndrome
(2015-09-01)Objectives: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sjögren's syndrome patients (SS patients), as well as their in vitro expression induced by ...