Coumarin derivatives as promising xanthine oxidase inhibitors

dc.creatorFais A.
dc.creatorEra B.
dc.creatorAsthana S.
dc.creatorSogos V.
dc.creatorMedda R.
dc.creatorSantana L.
dc.creatorUriarte E.
dc.creatorMatos M.J.
dc.creatorDelogu F.
dc.creatorKumar A.
dc.date.accessioned2020-09-02T22:17:22Z
dc.date.accessioned2022-11-08T20:22:17Z
dc.date.available2020-09-02T22:17:22Z
dc.date.available2022-11-08T20:22:17Z
dc.date.created2020-09-02T22:17:22Z
dc.date.issued2018
dc.identifier120, , 1286-1293
dc.identifier01418130
dc.identifierhttps://hdl.handle.net/20.500.12728/4414
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5144370
dc.languageen
dc.publisherElsevier B.V.
dc.subjectCoumarin derivatives
dc.subjectMolecular docking
dc.subjectXanthine oxidase inhibition
dc.subject3 heteroarylcoumarin derivative
dc.subject5,7 dihydroxy 3 (3' hydroxyphenyl)coumarin
dc.subjectallopurinol
dc.subjectarylcoumarin derivative
dc.subjectcoumarin derivative
dc.subjectmolecular scaffold
dc.subjectunclassified drug
dc.subjectxanthine oxidase
dc.subjectxanthine oxidase inhibitor
dc.subjectallopurinol
dc.subjectcoumarin
dc.subjectcoumarin derivative
dc.subjectenzyme inhibitor
dc.subject3T3 cell line
dc.subjectamino acid sequence
dc.subjectanimal cell
dc.subjectArticle
dc.subjectbinding site
dc.subjectcontrolled study
dc.subjectdrug safety
dc.subjectenzyme active site
dc.subjectenzyme binding
dc.subjectenzyme inhibition
dc.subjectIC50
dc.subjectmolecular docking
dc.subjectmouse
dc.subjectnonhuman
dc.subjectpharmacokinetics
dc.subjectphysical chemistry
dc.subjectantagonists and inhibitors
dc.subjectchemical structure
dc.subjectchemistry
dc.subjectstructure activity relation
dc.subjectAllopurinol
dc.subjectCatalytic Domain
dc.subjectCoumarins
dc.subjectEnzyme Inhibitors
dc.subjectMolecular Docking Simulation
dc.subjectMolecular Structure
dc.subjectStructure-Activity Relationship
dc.subjectXanthine Oxidase
dc.titleCoumarin derivatives as promising xanthine oxidase inhibitors
dc.typeArticle


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