Compact CIY model relationship with sustainability in urban regeneration projects

Abstract

The aims of the present study were to examine whether the pattern of syndecan-1 expression correlates with cellular proliferation index in desmoplastic ameloblastomas (DA), peripheral ameloblastomas (PA) and ameloblastic carcinomas (AC), and to compare with that previously reported for solid (SA) and unicystic (UA) variants of ameloblastoma. Immunohistochemistry was performed for syndecan-1 and Ki-67 in seven ameloblastomas (four DA and three PA) and three AC. Expression of syndecan-1 was related to the histological subtype of tumors and, in the case of malignancy, to lower expression levels observed in AC (22.5%) than in PA (47.5%) or DA (77.5%) (P < 0.05). Syndecan-1 expression correlated inversely with Ki-67 proliferative index: the expression was lower in both types of ameloblastomas (1.5% in DA and 6.4% in PA) than in AC (41.2%; P < 0.05). The present results suggest that the decrease in syndecan-1 expression and increase in the Ki-67 index observed in AC is in accordance with its higher aggressiveness as compared to the rare DA and PA. Interestingly, DA had a lower proliferation index as well as the highest levels of syndecan-1 expression. These data suggest that DA differ from the other types of intraosseous ameloblastomas but more studies are necessary to better understand the role of this protein as a marker in the biological behavior of the epithelial odontogenic neoplasms. " 2009 Japanese Society of Pathology.",,,,,,"10.1111/j.1440-1827.2009.02355.x",,,"http://hdl.handle.net/20.500.12104/40198","http://www.scopus.com/inward/record.url?eid=2-s2.0-63849234509&partnerID=40&md5=0c6da513c012f0a4b01d1c0ac08c2570",,,,,,"4",,"Pathology International",,"229

233",,"59",,"Scopus

WOS",,,,,,"Ameloblastic carcinoma; CD138; Desmoplastic ameloblastoma; Ki-67; Peripheral ameloblastoma; Syndecan-1",,,,,,"Comparative expression of syndecan-1 and Ki-67 in peripheral and desmoplastic ameloblastomas and ameloblastic carcinoma",,"Article" "42955","123456789/35008","Velázquez-Zamora, D.A., División de Neurociencias, Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jal, Mexico, Departamento de Biología Celular y Molecular, CUCBA, Universidad de Guadalajara, Guadalajara, Jal, Mexico; González-Ramírez, M.M., División de Neurociencias, Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jal, Mexico; Beas-Zárate, C., División de Neurociencias, Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jal, Mexico, Departamento de Biología Celular y Molecular, CUCBA, Universidad de Guadalajara, Guadalajara, Jal, Mexico; González-Burgos, I., División de Neurociencias, Centro de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jal, Mexico, Departamento de Biología Celular y Molecular, CUCBA, Universidad de Guadalajara, Guadalajara, Jal, Mexico, Laboratorio de Psicobiología, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro Social, Sierra Mojada #800, Col. Independencia 44340, Guadalajara, Jal, Mexico

Beas-Zárate, Carlos., Universidad de Guadalajara. Centro Universitario de Ciencias Biológicas y Agropecuarias",,"Velazquez-Zamora, D.A.

Gonzalez-Ramirez, M.M.

Beas-Zárate, Carlos

Gonzalez-Burgos, I.",,"2011",,"Working memory may involve context-dependent allocentric or own movement-dependent egocentric strategies. While allocentric working memory can be disrupted by N-methyl-D-aspartate (NMDA) blockage, the possible effects of NMDA receptor manipulation on the egocentric strategy have not been studied. Because dendritic spine plasticity in part underlies working memory-related behavioral efficiency, egocentric working memory performance was evaluated in adult rats following NMDA receptor blockade with 10 mg/kg of the NMDA-receptor antagonist CPP, i.p. Dendritic spine density and the proportion of different spine types (thin, stubby, mushroom, wide, branched and double) were assessed in third-layer pyramidal neurons of the dorsomedial prefrontal cortex, after behavioral testing. Working memory was evaluated by challenging the rats to resolve twelve trials per day in a single-day session over five consecutive days, in a "cross-arm" maze and according to a delayed match-to-sample procedure. In control animals, the dendritic spine density remained unchanged after behavioral testing, although the proportion of mushroom spines decreased while that of the branched spines increased. NMDA receptor blockade impaired the behavioral performance of rats and resulted in a decrease in dendritic spine density when compared to the control animals, and dendritic spine types were unchanged. These results suggest that behavioral efficiency of egocentric working memory is dependent on NMDA receptor activation, and that plastic changes in spine cytoarchitecture may play a key role in behavioral performance. © 2011 Elsevier B.V. All rights reserved.",,,,,,"10.1016/j.brainres.2011.06.018",,,,"http://www.scopus.com/inward/record.url?eid=2-s2.0-79960222211&partnerID=40&md5=e63bbbd6112f41cb708ac067b31f6e16

http://hdl.handle.net/20.500.12104/41176",,,,,,,,"Brain Research",,"101

108",,"1402",,"Scopus

WOS",,,,,,"CPP; Dendritic spine; Egocentric working memory; NMDA; Plasticity; Prefrontal cortex",,,,"Egocentric working memory impairment and dendritic spine plastic changes in prefrontal neurons after NMDA receptor blockade in rats",,,,"Article", "41946","123456789/35008",,"Soto-Avila, J.J., Servicio de Cirugía General, Hospital Civil de Guadalajara Fray Antonio Alcalde, Universidad de Guadalajara.; Gómez-Wong, M.E., Servicio de Cirugía General, Hospital Civil de Guadalajara Fray Antonio Alcalde, Universidad de Guadalajara.; Preciado-Hernández, F., Servicio de Cirugía General, Hospital Civil de Guadalajara Fray Antonio Alcalde, Universidad de Guadalajara.",,"Soto-Avila, J.J.

Gomez-Wong, M.E.

Preciado-Hernandez, F.",,"2006",,"BACKGROUND: The endoscopic placement of endoprostheses to decompress biliary obstruction is a commonly used treatment for malignant biliary diseases and is also used in the treatment of benign biliary strictures. Unusual complications of endoprosthesis placement have been described and include the migration of the stent. We present a case to share with the scientific community, an unusual complication secondary to the migration of a biliary stent that has not previously been reported to our knowledge. CASE REPORT: We present the case of a 47-year-old female with a diagnosis of benign papillary stenosis. The patient received a biliary endoprosthesis with clinical improvement. Later she underwent open cholecystectomy and common duct exploration. At consultation 18 months later, the patient presents with indistinct lower abdominal pain and dysuria. We performed imaging studies where the biliary stent was observed, partly in the sigmoid colon and partly in the bladder. The patient underwent surgery where a colovesical fistula was found and treated during the same surgical event. The patient was discharged succesfully.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40167","http://www.scopus.com/inward/record.url?eid=2-s2.0-34447637787&partnerID=40&md5=73454dac8a0090ce90eb64cafe4d79a1",,,,,,"6",,"Cirugia y cirujanos",,"473

475",,"74",,"Scopus",,,,,,,,,,,,"Colovesical fistula secondary to the migration of a biliary stent. Case report [Féstula colovesical secundaria a la migración de una endoprótesis biliar. Reporte de un caso.]",,"Article" "41949","123456789/35008","Gálvez-Gastélum, F.J., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; García-Báuelos, J.J., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; Beas-Zárate, C., Laboratory of Molecular and Cell Neurobiology, CIBO, University of Guadalajara, Mexico; Segura-Flores, A., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; González, H., Research and Pharmaceutical Development Laboratory, Pharmacology Department, University of Guadalajara, Mexico; Chaparro-Huerta, V., Laboratory of Molecular and Cell Neurobiology, CIBO, University of Guadalajara, Mexico; Salazar-Montes, A., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; Sandoval-Rodriguez, A.S., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; Bueno-Topete, M., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; Lucano-Landeros, S., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico; Medina-Preciado, D., OPD Civil Hospital, Guadalajara, Mexico; Gonzalez-García, I., OPD Civil Hospital, Guadalajara, Mexico; Armendariz-Borunda, J., Institute for Molecular Biology and Gene Therapy, CUCS, University of Guadalajara, Jalisco, Mexico, OPD Civil Hospital, Guadalajara, Mexico

Beas-Zárate, Carlos., Universidad de Guadalajara. Centro Universitario de Ciencias de la Salud",,"Galvez-Gastelum, F.J.

García-Bauelos, J.J.

Beas-Zárate, Carlos

Segura-Flores, A.

Gonzalez, H.

Chaparro-Huerta, V.

Salazar-Montes, A.

Sandoval-Rodriguez, A.S.

Bueno-Topete, M.

Lucano-Landeros, S.

Medina-Preciado, D.

Gonzalez-García, I.

Armendariz-Borunda, J.",,"2011",,"Capillarization of the sinusoid impedes the clearance of neurotoxic substances in liver fibrosis. These events may result in hepatic encephalopathy. Neurological and hepatic features of rats after bile duct ligation (BDL) supplemented with Manganese (BDLMn 2+) were examined. The 4-week-old BDL rats had elevated levels of ammonia and were concomitantly fed with 1 mg ml -1 of MnCl -2 in drinking water (BDL/Mn 2+). Five out of fifteen rats were killed and the serum, liver and brain tissue (striatum and substantia nigra) were recovered. Of the remaining BDL/Mn 2+-cirrhotic animals (n10), five were injected with a combination of Adenovirus-human plasminogen activator (Ad-huPA) and Adenovirus-matrix metalloproteinase-8 (Ad-MMP-8) (3 × 10 11+1.5 × 10 11 vector particles per kg), and five with 4.5 × 10 11 vector particles per kg of Adenovirus-?-galactosidase (Ad-?-Gal). This treatment was carried on for 10 days. The BDL/Mn 2+ rats displayed tremor, rigidity and gait abnormalities, which improved notably with combinatorial gene therapy, as well as motor coordination. Liver fibrosis was evidently less after treatment with Ad-huPAAd-MMP-8 (25%). In the brain (striatum), Ad-huPAAd-MMP-8 treatment rendered higher concentrations of dopamine compared with Ad-?-Gal-treated encephalopathic rats (210 and 162 ng g -1 of tissue, respectively). The BDL/Mn 2+ animals and controls treated with Ad-?-Gal showed abnormal morphology in astrocytes (gliosis) in striatum and substantia nigra, in which expressions of green fibrillar acidic protein and tyrosine hydroxylase were altered. These abnormalities decreased with Ad-huPAAd-MMP-8 treatment. Importantly, the latter animals showed an increment in sprouting of nervous fibers in substantia nigra. Combinatorial gene therapy improves neuroanatomical and neurochemical characteristics similar to human hepatic encephalopathy. © 2011 Macmillan Publishers Limited All rights reserved.",,,,,,"10.1038/gt.2010.107",,,,"http://www.scopus.com/inward/record.url?eid=2-s2.0-78650970733&partnerID=40&md5=b7b6da470818d8fb7a9606a8bf35cbeb

http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=20703313

http://hdl.handle.net/20.500.12104/40170",,,,,,"1",,"Gene Therapy",,"88

94",,"18",,"Scopus

WOS

MEDLINE",,,,"Index Medicus;Adenoviridae/ge [Genetics];Adenoviridae/me [Metabolism];Animals;Bile Ducts/me [Metabolism];Genetic Therapy/mt [Methods];Hepatic Encephalopathy/pa [Pathology];Hepatic Encephalopathy/th [Therapy];Humans;Liver/me [Metabolism];Liver/pa [Pathology];Liver Cirrhosis/me [Metabolism];Liver Cirrhosis/th [Therapy];Matrix Metalloproteinase 8/ad [Administration & Dosage];Matrix Metalloproteinase 8/ge [Genetics];Matrix Metalloproteinase 8/me [Metabolism];Plasminogen Activators/ad [Administration & Dosage];Plasminogen Activators/ge [Genetics];Plasminogen Activators/me [Metabolism];Rats;Rats, Inbred Strains;beta-Galactosidase/ge [Genetics];beta-Galactosidase/me [Metabolism]",,"fibrosis; metalloprotease; plasminogen",,,,"Combinatorial gene therapy induces regression of hepatic encephalopathy",,,,"Article", "41952","123456789/35008",,"Coguitchaichvili, A., Instituto de Geofísica, Univ. Nac. Autónoma de Mexico, Depto. de Paleomagnetismo/Geofisica, Mexico, DF 04510, Mexico; Alva-Valdivia, L.M., Instituto de Geofísica, Univ. Nac. Autónoma de Mexico, Depto. de Paleomagnetismo/Geofisica, Mexico, DF 04510, Mexico; Rosas-Elcuera, J., Centro de Ciencias de la Tierra, Universidad de Guadalajara, Apartado postal 4-045, Guadalajara 44840, Mexico; Urrutia-Fucugauchi, J., Instituto de Geofísica, Univ. Nac. Autónoma de Mexico, Depto. de Paleomagnetismo/Geofisica, Mexico, DF 04510, Mexico; Soler, A.-M., Instituto de Geofísica, Univ. Nac. Autónoma de Mexico, Depto. de Paleomagnetismo/Geofisica, Mexico, DF 04510, Mexico; Caballero, C., Instituto de Geofísica, Univ. Nac. Autónoma de Mexico, Depto. de Paleomagnetismo/Geofisica, Mexico, DF 04510, Mexico",,"Coguitchaichvili, A.

Alva-Valdivia, L.M.

Rosas-Elcuera, J.

Urrutia-Fucugauchi, J.

Soler, A.-M.

Caballero, C.",,"2003",,"Results of detailed paleomagnetic studies of the Upper Cretaceous Autlan volcanic sequence from the Sierra Cacoma area (Jalisco block, western Mexico) are reported. The 67.4 1.2 Ma whole-rock K-Ar date for these lavas and the magnetic polarity stratigraphy indicate that flows were emplaced after the Cretaceous Normal Superchron and just prior to the Cretaceous-Tertiary boundary. Fifteen sites (? 150 oriented samples) were collected along two vertical profiles. Rock-magnetic experiments permit identification of magnetic carriers and assessment of the paleomagnetic stability. Continuous susceptibility measurements versus temperature in most cases yield reasonably reversible curves with Curie points close to magnetite. Judging from the ratios of hysteresis parameters, all samples fall in the pseudo-single domain grain-size region, probably indicating a mixture of multi-domain and a significant amount of single-domain grains. Reliable paleomagnetic directions were obtained for 14 sites, corresponding to 2 normal and 12 reverse polarity sites. Lowermost flows in the sequence yield reverse polarity magnetization, and probably formed during Chron 31r of the reference geomagnetic polarity time scale. The remaining flows, including those belonging to radiometrically dated sites, correspond to Chron 30n. These tentative magnetic correlations suggest that the entire volcanic sequence was emplaced during a time span of about 2 Ma. The mean paleodirection obtained from 14 sites is Inc = 44.2 , Dec = 320.6 , k = 45, ? 95 = 6.0 . The mean inclination is in reasonably good agreement with the expected value for 65 and 70 Ma, as derived from reference poles for the North American craton. Declination is significantly different from expected (D = 345.8 for 65 Ma and D = 346.2 for 70 Ma), which suggests a counterclockwise tectonic rotation of about 25 for this region within the Jalisco block.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40173","http://www.scopus.com/inward/record.url?eid=2-s2.0-0345017706&partnerID=40&md5=b2c8ae7aad905a2b207a0cb3ddf58815",,,,,,"10",,"International Geology Review",,"886

897",,"45",,"Scopus

WOS",,,,,,,,,,,,"Combined paleomagnetic and petromagnetic study of the Upper Cretaceous volcanic sequence in Western Mexico: Implications for tectonics/magnetostratigraphy of the Jalisco block",,"Article" "41995","123456789/35008",,,"Arroyo Alejandre, Jesús",,"1998",,,,,,,,,,"0187-7674",,"http://hdl.handle.net/20.500.12104/40216",,"Español",,,,"63",,"Confines de relaciones internacionales y ciencia política",,"27-33",,"11",,"CLASE",,,,,,,,"Educación superior",,"Economía y posgrado",,,,"journalArticle", "41970","123456789/35008",,"Jimenez-Dominguez, B., Urban Studies Center, University of Guadalajara, Centro de Estudios Urbanos CUCSH/UdG, Garibaldi 1859 CP 44650, Guadalajara, Mexico",,"Jimenez-Dominguez, B.",,"2013",,"The ruling model of urban growth is clearly unsustainable due to overuse of natural resources and consequent environment. This had led to the discussion on urban sustainability regeneration projects from participative approaches to propose a compact city model as an alternative to the ruling model of sprawl oriented city. In practice, compact city model would be the condition of a sustainable city, because this city will consume less energy, will have more cleaner air, less traffic problems, more public spaces and will be a more livable and pedestrian oriented city. A compact city is defined as a denser, socially diverse city, with people living around neighborhoods and where social and economic activities are overcome. But this compact city perspective could be better defined, since in practice it presents different problems derived from a contradiction between urban desirability and suburban habitability, and it is discussed herein as such, showing some contradictory results. As an example, a local study of a compact city based project failure is described. " 2013 by Nova Science Publishers, Inc. All rights reserved.