Articulo
Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells
Fecha
2015Registro en:
1110397
WOS:000366402000009
Institución
Resumen
Heme-oxygenase 1 (HO-1) prevents T cell-mediated inflammatory disease by producing carbon monoxide (CO) and impairing DC immunogenicity. However, the cellular mechanisms causing this inhibition are unknown. Here, we show that CO impairs mitochondrial func