Articulo
Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes
Fecha
2008Registro en:
13980001
WOS:000255067400049
no scielo
eid=2-s2.0-45549102847
Institución
Resumen
Accumulation of extracellular amyloid beta peptide (Abeta), generated from amyloid precursor protein (APP) processing by beta- and gamma-secretases, is toxic to neurons and is central to the pathogenesis of Alzheimer disease. Production of Abeta from APP