Exosomes from bulk and stem cells from human prostate cancer have a differential microrna content that contributes cooperatively over local and pre-metastatic niche.

Abstract

The different prostate cancer (PCa) cell populations (bulk and cancer stem cells, CSCs) release exosomes that contain miRNAs that could modify the local or premetastatic niche. The analysis of the differential expression of miRNAs in exosomes allows eval