Artículo de revista
No Relationship Between Patent Foramen Ovale and Migraine Frequency
Fecha
2016Registro en:
Headache, Volumen 56, Issue 9, 2018, Pages 1466-1473
15264610
00178748
10.1111/head.12945
Autor
Larrosa, Davinia
Ramón, César
Alvarez, Rocío
Martínez-Camblor, Pablo
Cernuda, Eva
Pascual, Julio
Institución
Resumen
© 2016 American Headache SocietyBackground: Pathophysiology of migraine is not fully known. A link has been proposed between migraine and patent foramen ovale (PFO). However, there are conflicting data regarding the causal relationship between PFO and migraine. Objective: To test a potential association between migraine frequency and PFO by way of an observational, single-center, case-controlled study. Methods: We studied a total of 130 chronic migraine (CM) and 53 episodic migraine (EM) patients. Transcranial Doppler with agitated saline injection was used to evaluate the presence and degree of PFO. PFO was judged to be present if any signal was detected. The degree of PFO during rest and Valsalva was quantified as follows: small (1–10 microbubbles [MB]), medium (10–25 MB), or large (>25 MB with shower or curtain pattern). PFO detected at rest were considered permanent, while those detected during Valsalva maneuver were classified as latent. Results: The prevalence of PFO was similar