Artículo de revista
Congenital malformations among offspring of diabetic women Malformaciones congénitas en hijos de madres con diabetes gestacional Malformaciones congénitas en hijos de madres con diabetes gestacional
Fecha
2005Registro en:
Revista Medica de Chile, Volumen 133, Issue 5, 2018, Pages 547-554
00349887
07176163
Autor
Herrera, Julio Nazer
Huidobro, Moira García
Ovalle, Lucía Cifuentes
Institución
Resumen
Background: The risk of congenital malformations is two to three times higher among women with diabetes mellitus before pregnancy. Gestacional diabetes is emerging as a risk factor for malformations. Aim: To study the rate and type of congenital malformations among offspring of women with pre-gestational or gestational diabetes. Material and methods: A search in the databases of the Collaborative Latin American Study for Congenital Malformations and of the Neonatology Unity of The University of Chile Clinical Hospital. All births from January 1998 through June 2004 were investigated. Results: In the study period, 13,965 births occurred, of which 0.7% were stillbirths and 8.1% had malformations. A total of 295 women (2.1%) had diabetes (gestational diabetes in 1.8% and pre gestational diabetes in 0.3%). The prevalence of congenital malformations was 14% and 18.3% among offspring of mothers with pre-gestational and gestational diabetes, respectively (p=NS). The prevalence of congenital m