Science, Technology & Innovation Policy (STIP) is an important policy instrument particularly in the developing countries. India also has recognized the role of science, technology and innovation in development as early as 1958 but still trails behind its peer Brazil, China and the Asian tiger Singapore. Considering strong correlation between research and development investment and growth based on existing studies, this paper brings forth the present situation of India in investment and its influence on the performance of the economy vis-à-vis the three countries. This paper studies the STIP 2013 in detail and reports the contribution of the Department of Science and Technology in India. The main conclusion of this paper is the recommendation for incorporation of entrepreneurship in STIP based on global best practices, which can be achieved by government’s involvement as a venture capitalist to seed and support innovations, increasing transparency and incorporating entrepreneurial curriculum.