The purpose of this chapter is to present a case study for evaluating the competences knowledge, skills, and attitudes applied by students in Higher Education by using m-learning devices in a course taught in an online distance education. The research question was. Which skills do the students need to learn through m-learning devices? Two variables used in this study were m-learning and learning technology skills. The results shows that m-learning becomes an extension, addition and/or evolution of online studying and that the student requires a set of basic knowledge and skills to handle cell phones and iPods as learning tools. Students also develop skills in computing, communication, productivity, relationships, leadership, self-study while being involved in a study mode such as mobile learning. Students also require competences such as self-management, evaluation and selection of information, creativity, communication and collaborative work.