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VIP treatment prevents embryo resorption by modulating efferocytosis and activation profile of maternal macrophages in the CBAxDBA resorption prone model
(Nature Publishing Group, 2016-01)
Successful embryo implantation occurs followed by a local pro-inflammatory response subsequently shifted toward a tolerogenic one. VIP (vasoactive intestinal peptide) has embryotrofic, anti-inflammatory and tolerogenic ...
Cyclosporin A-treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation
(Sociedad de Biología de Chile, 2010)
Glicómica de la respuesta inmune: El universo de glicanos y lectinas en microambientes inflamatorios y neoplásicosGlycomics of the immune response: the universe of glycans and lectins in inflammatory and neoplasic microenvironmentsGlicômica da resposta imune: o universo de glicanos e lectinas em microambientes inflamatórios e neoplásicos
(Federación Bioquímica de la Provincia Buenos Aires, 2011-12)
Las galectinas, una familia de lectinas que reconocen glico-conjugados específicos en la superficie celular y la matriz, participan en diversos procesos biológicos como reguladores de la ho-meostasis de la respuesta inmune ...
Autologous dendritic cells prolong allograft survival through tmem176b-dependent antigen cross-presentation
(Wiley Blackwell Publishing, Inc, 2014-04-14)
The administration of autologous (recipient-derived) tolerogenic dendritic cells (ATDCs) is under clinical evaluation. However, the molecular mechanisms by which these cells prolong graft survival in a donor-specific manner ...
Immunobiotic Lactobacillus jensenii modulates toll-like receptor 4-induced inflammatory response via negative regulation in porcine antigen presenting cells
(American Society for Microbiology, 2012-05-09)
Previously, we demonstrated that Lactobacillus (L.) jensenii TL2937 attenuates the inflammatory response triggered by activation of toll-like receptor (TLR)-4 in porcine intestinal epithelial cells. In view of the critical ...
Viral induction and targeted inhibition of galectin-1 in EBV + posttransplant lymphoproliferative disorders
(American Society Of Hematology, 2011-06)
Posttransplant lymphoproliferative disorders (PTLDs) are potentially fatal, EBVdriven B-cell malignancies that develop in immunocompromised solid organ or hematopoietic stem cell recipients. In PTLD, the expression of EBV ...
Turning 'sweet' on immunity: galectin–glycan interactions in immune tolerance and inflammation
(Macmillan Publisher Limited, 2009-05)
The function of deciphering the biological information encoded by the glycome, which is the entire repertoire of complex sugar structures expressed by cells and tissues, is assigned in part to endogenous glycan-binding ...
It takes guts for tolerance: The phenomenon of oral tolerance and the regulation of autoimmune response
(ELSEVIER SCIENCE BV, 2009)
The intestinal tract is a peculiar environment due to its constant contact with the microbiota agents, food antigens and other molecules. Such exposure requires the establishment of important regulatory mechanisms in order ...
'Sweetening' Pregnancy: Galectins at the Fetomaternal Interface
(Wiley Blackwell Publishing, Inc, 2013-04-14)
Successful mammalian pregnancy relies upon acceptance of a semi-allogeneic fetus by the maternal immune system. Lessons learned from studies on protective immunity to microbial infections and tumours, prevention of ...
Prostaglandins in semen compromise the immune response against sexually transmitted pathogens
(Elsevier, 2014-05)
Seminal plasma is not just a spermatozoa carrier. It induces the expression of inflammatory cytokines and chemokines and a massive infiltration of neutrophils, monocytes and dendritic cells in the female genital mucosa ...