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Short-term lipopolysaccharide stimulation indeces differentiation of murine bone marrow-derived dentritic cells into tolerogenic phenotype
(2007)
Dendritic cells (DCs) are professional, antigen-presenting cells, which induce and regulate T cell reactivity. DCs are crucial in innate and adaptive immune responses, and are also involved in central and peripheral tolerance ...
Multiple Tolerization Reduces Antibody Binding Against Tolerogen Cells: Implications for the Production of Monoclonal Antibodies
(2018-04-01)
We report an immunization technique that can update the production of monoclonal antibodies (mAbs): the multiple tolerization subtractive immunization (MTSI). A total of 10 BALB/C mice were used. Animals in group 1 received ...
Nitric Oxide Plays A Key Role In The Suppressive Activity Of Tolerogenic Dendritic Cells
(CHIN SOCIETY IMMUNOLOGYBEING, 2015)
Dexamethasone and monophosphoryl lipid a-modulated dendritic cells promote antigen-specific tolerogenic properties on naive and memory CD4+ T cells
(Frontiers Media S.A., 2016)
© 2016 Maggi, Schinnerling, Pesce, Hilkens, Catalán and Aguillón. Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and ...
The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype on DCs
(Academic Press, 2016)
© 2016 The Authors As it has been established that demethylation of lysine 27 of histone H3 by the lysine-specific demethylase JMJD3 increases immune responses and thus elicits inflammation, we hypothesize that inhibition ...
Oral tolerance and OVA-induced tolerogenic dendritic cells reduce the severity of collagen/ovalbumin-induced arthritis in mice
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2012)
Cyclosporine preconditions dendritic cells during differentiation and reduces IL-2 and IL-12 production following activation: A potential tolerogenic effect
(ELSEVIER, 2003-11)
The mode of action of cyclosporine (CsA) has been ascribed to its capacity to inhibit IL-2 and IFNgamma production by T cells, two cytokines implicated in allograft rejection. Recently, it has been reported that upon ...
Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific T-Cell Responses and IgE Production
(2014)
Natural rubber latex (NRL; Hevea brasiliensis) allergy is an IgE-mediated reaction to latex proteins. When latex glove exposure
is the main sensitizing agent, Hev b 5 is one of the major allergens. Dendritic cells (DC), ...