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Analysis of HCV quasispecies dynamic under selective pressure of combined therapy
(2013-02-01)
Background: The quasispecies composition of Hepatitis C virus (HCV) could have important implications with regard to viral persistence and response to interferon-based therapy. The complete NS5A was analyzed to evaluate ...
Mitochondrial genome sequence of the Brazilian luminescent click beetle Pyrophorus divergens (Coleoptera: Elateridae): Mitochondrial genes utility to investigate the evolutionary history of Coleoptera and its bioluminescence
(2007-12-15)
The Coleoptera order is the richest group among Metazoa, but its phylogenetics remains incompletely understood. Among Coleoptera, bioluminescence is found within the Elateroidea, but the evolution of this character remains ...
A new tetracycline resistance determinant cloned from Proteus mirabilis
(Elsevier B.V., 1998-11-26)
The chromosomal inducible Tc-r determinant from Proteus mirabilis was cloned and the nucleotide sequence of both the structural and repressor genes determined. the deduced amino acid sequence of the structural protein shows ...
Molecular phylogenetic relationships and phenotypic diversity in miniaturized toadlets, genus Brachycephalus (Amphibia: Anura: Brachycephalidae)
(2011-10-01)
Toadlets of the genus Brachycephalus are endemic to the Atlantic rainforests of southeastern and southern Brazil. The 14 species currently described have snout-vent lengths less than 18. mm and are thought to have evolved ...
Detection of Paracoccidioides spp. in environmental aerosol samples
(2013-01-01)
Taking into account that paracoccidioidomycosis infection occurs by inhalation of the asexual conidia produced by Paracoccidioides spp. in its saprobic phase, this work presents the collection of aerosol samples as an ...
Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus
(2009-01-01)
Human respiratory syncytial virus (HRSV) is the major cause of lower respiratory tract infections in children under 5 years of age and the elderly, causing annual disease outbreaks during the fall and winter. Multiple ...
Co-infecção por vírus dengue, sorotipos 1 e 4, em paciente de cidade de porte médio no Brasil
(2013-07-01)
The natural co-infection with dengue virus can occur in highly endemic areas where different serotypes have been observed for many years. We report one case of DENV-1/DENV-4 co-infection in human serum detected by molecular ...
Cloning and expression of the cDNA encoding rat granulocyte colony-stimulating factor
(1996-10-10)
Granulocyte colony-stimulating factor (G-CSF) acts on precursor hematopoietic cells to control the production and maintenance of neutrophils. Recombinant G-CSF (re-G-CSF)is used clinically to treat patients with neutropenia ...
Myostatin (GDF8) single nucleotide polymorphisms in Nellore cattle
(Funpec-editora, 2009-01-01)
The myostatin gene, also known as GDF8 (growth differentiation factor 8), is located on bovine chromosome 2 (BTA2); it has three exons and two introns. Myostatin is specifically expressed during embryonic development and ...
Development and validation of a D-loop mtDNA SNP assay for the screening of specimens in forensic casework
(2013-05-01)
Mitochondrial DNA (mtDNA) analysis is usually a last resort in routine forensic DNA casework. However, it has become a powerful tool for the analysis of highly degraded samples or samples containing too little or no nuclear ...