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Inorganic mercury in mammary cells: viability, metal uptake but efflux?
(Springer, 2017-11)
The viability, cellular uptake and subcellular distribution of heavy metal Hg, were determined in human mammary cell lines (MCF-7, MDA-MB-231 and MCF-10A). It was observed that Hg had the capacity of being excluded from ...
Cytotoxic and Antitumor Activity of some Coumarin Derivatives
(SAGE Publications, 2016-09)
Several natural and synthetic coumarins were assayed against different cancer cell lines. Four of them have shown cytotoxicity against a panel of three human solid tumor cell lines (HeLa, T-47D, and WiDr) and a clearly ...
4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines
(Springer, 2016-10)
Chronic myeloid leukemia (CML) is a myeloproliferative syndrome characterizedby the presence of the Philadelphia chromosome which encodes a constitutivelyactivated tyrosine kinase (BCRABL).The first line treatment for CML ...
Dose-independent genotoxic response in A549 cell line exposed to fungicide Iprodione
(Springer, 2020-11)
The fungicide Iprodione is widely applied in vegetables and raises concern for human health. The A549 human lung carcinoma cell line is a suitable model for assessing the toxicological effects of drugs. The goal of this ...
Characterization of cellular states of CHO-K1 suspension cell culture through cell cycle and RNA-sequencing profiling
(Elsevier Science, 2018-11)
Chinese hamster ovary (CHO) derived cell lines are the preferred host system for the production of therapeutic proteins. The aim of this work was to explore the regulation of suspension-adapted CHO-K1 host cell line ...
Maintenance of murine embryonic stem cells' self-renewal and pluripotency with increase in proliferation rate by a bovine granulosa cell line-conditioned medium
(Mary Ann Liebert, 2011-08)
Murine embryonic stem cells (mESCs) are pluripotent cells that can be propagated in an undifferentiated state in continuous culture on a feeder layer or without feeders in the presence of leukemia inhibitory factor (LIF). ...
Magnetic-Activated Cell Sorting for the Fast and Efficient Separation of Human and Rodent Schwann Cells from Mixed Cell Populations
(Humana Press, 2018)
This volume presents an assortment of traditional and emerging experimental procedures relevant to Schwann cell research. The chapters are divided into four parts. Part I contains protocols for in vitro culture, purification, ...
Effect of histamine on the expression of metalloproteinases and cell adhesion in breast cancer cell lines
(Springer, 2009-04)
Changes in cell adhesion and matrix metalloproteinases production (MMPs) are pivotal for tumour progression to occur. MMPs degrade extracellular matrix, MMP2, MMP9 and MMP7 being associated with the malignant potential of ...
Epithelial Sodium Channel in a Human Trophoblast Cell Line (BeWo)
(Springer, 2008-06)
The present study was performed to assay sodium currents in BeWo cells. These cells comprise a human trophoblast cell line which displays many of the biochemical and morphological properties similar to those reported for ...