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Potential impact of interfacial composition of proteins and polysaccharides stabilized emulsions on the modulation of lipolysis. The role of bile salts
(Elsevier, 2017-07)
Important insights into the role of interfacial composition and structure in controlling the digestion of oil-water emulsions have been gained in the last decade. The driving interest relies on: i) the necessity of controlling ...
Effects of bile acid sequestration on hepatic steatosis in obese mice
(Mexican Association of Hepatology, 2014-01)
Background: Bile acid sequestration (BAS) with resins has shown antidiabetic effects in both humans and animals. Since hepatic steatosis is commonly associated to type 2 diabetes mellitus and the effects of BAS on steatosis ...
Impact of bile salt adaptation of Lactobacillus delbrueckii subsp. lactis 200 on its interaction capacity with the gut
(Elsevier Science, 2011-10)
In a previous work, bile-salt-resistant derivatives were obtained from non-intestinal lactobacilli. The aim of this work was to investigate the impact of bile adaptation of Lactobacillus delbrueckii subsp. lactis 200 on ...
Hybrids of Cinchona Alkaloids and Bile Acids as Antiparasitic Agents against Trypanosoma cruzi
(Molecular Diversity Preservation International, 2019-08)
The current chemotherapy of Chagas disease needs to be urgently improved. With this aim, a series of 16 hybrids of Cinchona alkaloids and bile acids were prepared by functionalization at position C-2 of the quinoline nucleus ...
Anticholestatic mechanisms of ursodeoxycholic acid in lipopolysaccharide-induced cholestasis
(Pergamon-Elsevier Science Ltd, 2019-10)
Lipopolysaccharide (LPS) from Gram (-) bacteria induces inflammatory cholestasis by impairing the expression/localization of transporters involved in bile formation (e.g., Bsep, Mrp2). Therapeutic options for this disease ...
Synthesis of steroidal quinones and hydroquinones from bile acids by Barton radical decarboxylation and benzoquinone addition: Studies on their cytotoxic and antifungal activities
(Elsevier Science Inc, 2012-01)
Twelve new hydroquinones and quinones (4a-c to 7a-c) derived from free or peracetylated bile acids were prepared by a Barton decarboxylation reaction, with subsequent trapping of the resulting free radical by benzoquinone. ...
Papillary Adenocarcinoma of the Extrahepatic Bile Duct in a Holstein Cow
(American College of Veterinary Pathologists, 2005-01)
A 15-year-old female Holstein cow was presented with a history of anorexia and weight loss. Abnormal physical examination findings included poor body condition, dehydration, icterus, and photodermatitis on nonpigmented ...
Choleretic Properties of Baccharis spicata Aerial Parts Extracts in Male Wistar Rats
(Springer, 2020-02)
Many Baccharis species, Asteraceae, called “carquejas” are traditional folk herbs used for the treatment of hepatic disorders in South American countries. Baccharis articulata (Lam.) Pers. and B. crispa Spreng. are included ...
Technological characterization and survival of the exopolysaccharide-producing strain Lactobacillus delbrueckii subsp. lactis 193 and its bile-resistant derivative 193+ in simulated gastric and intestinal juices
(Cambridge University Press, 2011-07)
The capacity of lactic acid bacteria to produce exopolysaccharides (EPS) conferring microorganisms a ropy phenotype could be an interesting feature from a technological point of view. Progressive adaptation to bile salts ...
Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses
(Elsevier Science Inc, 2019-03)
Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal ...