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Dietary compound resveratrol is a pan-BET bromodomain inhibitor
(2017-11-01)
The chemopreventive and anticancer effects of resveratrol (RSV) are widely reported in the literature. Specifically, mechanisms involving epigenetic regulation are promising targets to regulate tumor development. Bromodomains ...
Serine proteases in neutrophil extracellular traps exhibit anti-Respiratory Syncytial Virus activity
(2022-05-01)
Human respiratory syncytial virus (hRSV) is an infectious agent in infants and young children which there are no vaccines or drugs for treatment. Neutrophils are recruited for airway, where they are stimulated by hRSV to ...
Experimental evidence and molecular modeling of the interaction between hRSV-NS1 and quercetin
(2016-04-01)
Human Respiratory Syncytial Virus is one of the major causes of acute respiratory infections in children, causing bronchiolitis and pneumonia. Non-Structural Protein 1 (NS1) is involved in immune system evasion, a process ...
Optimized Extraction of Resveratrol from Arachis repens Handro by Ultrasound and Microwave: A Correlation Study with the Antioxidant Properties and Phenol Contents
(2016-01-01)
The vegetal species Arachis repens, commonly known as peanut grass, was studied and, for the first time, we detected the presence of the bioactive compound trans-resveratrol (t -RSV). We compared the efficiency of three ...
Molecular Characterization of Strains of Respiratory Syncytial Virus Identified in a Hematopoietic Stem Cell Transplant Outpatient Unit Over 2 Years: Community or Nosocomial Infection?
(ELSEVIER SCIENCE INC, 2008)
Respiratory syncytial virus (RSV) is recognized as the leading cause of nosocomial respiratory infection among hematopoietic stem cell transplant (HSCT) recipients, causing considerable morbidity and mortality. RSV is ...
Depletion of circulating regulatory T cells during severe respiratory syncytial virus infection in young children
(American Thoracic Society, 2014-04)
Respiratory syncytial virus (RSV) is the main cause of viral lower respiratory tract illness in infancy and early childhood. Each year, RSV is estimated to cause 34 million cases of lung infection, and the deaths of up to ...
Neutrophil extracellular traps possess anti-human respiratory syncytial virus activity: Possible interaction with the viral F protein
(2018-06-02)
Human respiratory syncytial virus (hRSV) is one of the main etiological agents of diseases of the lower respiratory tract, and is often responsible for the hospitalization of children and the elderly. To date, treatments ...
The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus
(2007)
Our aim was to obtain knowledge of how meteorological conditions affect community epidemics of respiratory syncytial virus (RSV) infection. To this end we recorded year-round RSV activity in nine cities that differ markedly ...
Respiratory syncytial virus (RSV) pneumonia in a southern muriqui (Brachyteles arachnoides)
(WILEY-BLACKWELLHOBOKEN, 2012)
Background An adult male Brachyteles arachanoides, kept in captivity since 1990, was found dead without apparent clinical evidence. Methods Necropsy report, histopathology, immunohistochemistry, and ultrastructural examination ...