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Interleukin-17 mediated immunity during infections with Trypanosoma cruzi and other protozoans
(Elsevier Science, 2020-05)
Host resistance during infection with Trypanosoma cruzi, and other protozoans, is dependent on a balanced immune response. Robust immunity against these pathogens requires of the concerted action of many innate and adaptive ...
Simultaneous detection of four protozoan parasites on leafy greens using a novel multiplex PCR assay
(Academic Press Ltd - Elsevier Science Ltd, 2019-12)
Pathogen contamination of fresh produce presents a health risk for consumers; however, the produce industry still lacks adequate tools for simultaneous detection of protozoan parasites. Here, a simple multiplex PCR (mPCR) ...
A functional analysis of the cyclophilin repertoire in the protozoan parasite trypanosoma cruzi
(MDPI AG, 2018-10)
Trypanosoma cruzi is the etiological agent of Chagas disease. It affects eight million people worldwide and can be spread by several routes, such as vectorborne transmission in endemic areas and congenitally, and is also ...
Immunity to Protozoan Parasites
(Hindawi, 2012)
ATPe dynamics in protozoan parasites. Adapt or Perish
(Multidisciplinary Digital Publishing Institute, 2018-12-27)
In most animals, transient increases of extracellular ATP (ATPe) are used for physiological signaling or as a danger signal in pathological conditions. ATPe dynamics are controlled by ATP release from viable cells and cell ...
DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide
(American Society for Microbiology, 2001-04)
The activation of innate immune responses by genomic DNA from bacteria and several nonvertebrate organisms represents a novel mechanism of pathogen recognition. We recently demonstrated the CpG-dependent mitogenic activity ...
Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia
(Wiley Blackwell Publishing, Inc, 2017-09)
Our understanding of protein and lipid trafficking in eukaryotic cells has been challenged by the finding of different forms of compartmentalization and cargo processing in protozoan parasites. Here, we show that, in the ...