Buscar
Mostrando ítems 11-14 de 14
Sustained-release hydrogels of ivermectin as alternative systems to improve the treatment of cutaneous leishmaniasis
(Future Medicine, 2020-12)
Leishmaniasis is a neglected tropical disease and its cutaneous form manifests as ulcers or nodules, generally in exposed parts of the body. This work aimed to develop ivermectin (IVM) thermosensitive hydrogels as topical ...
Praziquantel systems with improved dissolution rate obtained by high pressure homogenization
(Elsevier Science, 2018-12-01)
Praziquantel (PZQ), an antihelmintic agent commonly administered to humans and cattle, has low aqueous solubility, which compromises its bioavailability and efficacy. The purpose of this study was to develop a new formulation, ...
Nanocrystals of novel valerolactam-fenbendazole hybrid with improved in vitro dissolution performance
(Springer, 2020-10)
Valero-fenbendazole (VAL-FBZ) is a novel hybrid compound with in vitro anthelmintic activity, designed and synthesized to address the global problem of resistance to anthelmintic compounds. This new molecule derives from ...