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Effect of oral administration of a continuous 18 day regimen of meloxicam on ovulation: experience of a randomized controlled trial
(Elsevier, 2014)
Background: Cyclooxygenase-2 (COX-2) is expressed in all female reproductive organs. Therefore, inhibitors of COX-2 may affect
reproductive function. We evaluated the effect of extended administration of meloxicam on ...
A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. "ARAMIA"
(2006-09-07)
Background: The raising prevalence of type-2 diabetes mellitus and obesity has been recognized as a major problem for public health, affecting both developed and developing countries. Impaired fasting plasma glucose has ...
Severity of Candida-associated denture stomatitis is improved in institutionalized elders who consume Lactobacillus rhamnosus SP1
(Blackwell Publishing, 2019)
Background: This study aimed to determine the effect of the consumption of a probiotic on the clinical characteristics of Candida-associated denture stomatitis (DS) and to determine the impact of a protocol of self-care ...
Efficacy of andrographolide in not active progressive multiple sclerosis: a prospective exploratory double-blind, parallel-group, randomized, placebo-controlled trial
(BMC, 2020)
Background Multiple sclerosis (MS) is a chronic immune mediated disease and the progressive phase appears to have significant neurodegenerative mechanisms. The classification of the course of progressive MS (PMS) has been ...
The change of teeth color, whiteness variations and its psychosocial and selfperception effects when using low vs. high concentration bleaching gels: a one-year follow-up
(BMC, 2020)
Background: Dental bleaching in traditional concentrations generates greater sensitivity. In this respect, new systems of lower concentration of hydrogen peroxide for tooth bleaching appeared, with color stability unknown ...
Effect of Oral Eliglustat on Splenomegaly in Patients With Gaucher Disease Type 1. The ENGAGE Randomized Clinical Trial
(American Medical AssociationEstados Unidos, 2015-02-17)
Importance Gaucher disease type 1 is characterized by hepatosplenomegaly, anemia, thrombocytopenia, and skeletal disease. A safe, effective oral therapy is needed.
Objective To determine whether eliglustat, a novel ...
Uso de los anticoagulantes orales directos en la práctica clínica
(Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina, 2016-04-01)
Los anticoagulantes orales directos surgieron en respuesta a la búsqueda de un anticoagulante ideal después de que la warfarina fuera por mucho tiempo el único disponible. Los inhibidores del factor X activado —rivaroxabán ...
Tofacitinib versus etanercept or placebo in patients with moderate to severe chronic plaque psoriasis: patient-reported outcomes from a Phase 3 study
(Wiley-Blackwell, 2016)
BackgroundTofacitinib is an oral Janus kinase inhibitor that is being investigated for psoriasis. Psoriasis impacts on physical and psychological well-being; improvements in health-related quality of life (HRQoL) with ...
Estudio de biodisponibilidad relativa entre dos formulaciones orales de micofenolato mofetilo en voluntarios sanos
(2011)
Background: The bioequivalence of different formulations of a same pharmaceutical
product must be tested empirically. Aim: To evaluate the relative bioavailability
for an oral formulation of mycophenolate mofetil (MMF) ...
Clinical Effects of Lactobacillus rhamnosus in Non-Surgical Treatment of Chronic Periodontitis: A Randomized Placebo-Controlled Trial With 1-Year Follow-Up
(Amer Physical Soc., 2016)
Background: Probiotics are living microorganisms that provide beneficial effects for the host when administered in proper quantities. The aim of this double-masked placebo-controlled parallel-arm randomized clinical trial ...