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Magnetic separation of peripheral nerve-resident cells underscores key molecular features of human Schwann cells and fibroblasts: an immunochemical and transcriptomics approach
(Nature Publishing Group, 2020-12-28)
Nerve-derived human Schwann cell (SC) cultures are irreplaceable models for basic and translational research but their use can be limited due to the risk of fibroblast overgrowth. Fibroblasts are an ill-defined population ...
Fluorescence properties of curcumin-loaded nanoparticles for cell tracking
(Dove Press, 2018-12)
Background: Posttransplant cell tracking, via stem cell labeling, is a crucial strategy for monitoring and maximizing benefits of cell-based therapies. The structures and functionalities of polysaccharides, proteins, and ...
DMT1 iron uptake in the PNS: bridging the gap between injury and regeneration
(Royal Society Of Chemistry, 2015-09)
Previous work by our group demonstrated the key role of iron in Schwann cell (SC)maturation through an increase in cAMP, PKA activation and CREB phosphorylation. These studies opened the door to further research on a ...
Photoactivatable Adhesive Ligands for Light-Guided Neuronal Growth
(Wiley VCH Verlag, 2018-06-06)
Neuro-regeneration after trauma requires growth and reconnection of neurons to reestablish information flow in particular directions across the damaged tissue. To support this process, biomaterials for nerve tissue ...
In Situ, Light-Guided Axon Growth on Biomaterials via Photoactivatable Laminin Peptidomimetic IK(HANBP)VAV
(American Chemical Society, 2018-12)
The ability to guide the growth of neurites is relevant for reconstructing neural networks and for nerve tissue regeneration. Here, a biofunctional hydrogel that allows light-based directional control of axon growth in ...