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Expression and function of non-neuronal GABA transporters in human lymphocytes
(Asian Network for Scientific Information, 2017-01-15)
Background: Neurotransmitters not only play a key role in neuronal communication but also coordinate cell functions in non-neuronal cells, such as immune cells. Previous research reported a complete GABAergic system in ...
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Human coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV) and 2019 novel
coronavirus (2019-nCoV, also known as SARS-CoV-2), lead global epidemics with high morbidity and mortality.
However, ...
Envelhecimento e medicamentos: um panorama de solicitações junto ao Ministério Público de um município do estado de São Paulo
(Universidade Federal de São CarlosUFSCarCâmpus São CarlosGerontologia - Gero, 2020-12-01)
Introduction: The number of Brazilian elderly people has been increasing in recent decades. However, there is also a significant increase in spending on health and greater consumption of medicines. Guaranteeing the right ...
Manejo farmacológico e não farmacológico da xerostomia induzida por radioterapia: uma revisão sistemática seguida de metanálise em redePharmacological and non-pharmacological management of radiotherapy-induced xerostomia: a systematic review and network meta-analysis.
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Ciências da Saúde, 2021)
Efficacy of pharmacological therapies for the prevention of fractures in postmenopausal women: A network meta-analysis
(Oxford University Press, 2019)
Background: Osteoporosis and osteopenia are associated with increased fracture incidence in postmenopausal women. We aimed to determine the comparative effectiveness of various available pharmacological therapies. Methods: ...
Resting state networks characterization for individual subjects assessment
(2018-05-30)
Cumulative research in hemodynamic brain activity measured in resting state (RS) using functional magnetic resonance imaging (fMRI) suggests that healthy brain dynamics are distributed on large-scale spatial resting state ...
Exploração racional da rede metabólica de Xylaria sp. visando à produção de metabólitos de interesse farmacológico através de ferramentas quimiométricas e técnicas de desreplicaçãoRational exploitation of the network of metabolic Xylaria sp. aimed at interest metabolites production pharmacologic through chemometric tools and techniques dereplication
(Universidade Estadual Paulista (Unesp), 2016)
In silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, and artificial neural networks reveal potential therapeutic targets for drug repurposing against COVID-19
(Frontiers Media, 2021)
Background: There is pressing urgency to identify therapeutic targets and drugs that
allow treating COVID-19 patients effectively.
Methods: We performed in silico analyses of immune system protein interactome
network, ...
Asma: suas origens, seus mecanismos inflamatórios e o papel do corticosteróideAsthma: its origins, inflammatory mechanisms and the role of the corticosteroid
(Centro de Referência Prof. Hélio Fraga , Secretaria de Vigilância em Saúde, Ministério da Saúde, 2015)