Buscar
Mostrando ítems 21-30 de 302
Role of TNF-α, IL-1β and IL-6 in the local tissue damage induced by Bothrops asper snake venom: an experimental assessment in mice
(2005-02)
The role of the cytokines TNF-α, IL-1β and IL-6 in the acute local pathological effects induced by Bothrops asper snake venom was assessed in mice. Intramuscular injection of this venom induced increments in IL-1β and IL-6 ...
An MTT-based method for the in vivo quantification of myotoxic activity of snake venoms and its neutralization by antibodies
(1993-05)
The reduction of the tetrazolium compound MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide) was used as the basis for the development of a simple method for the quantitative estimation of metabolically ...
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
(2009-12-01)
Envenomations by Bothrops asper are often associated with complex and severe local pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and hemorrhage. The pathogenesis of these alterations ...
THE ABILITY OF SPECIFIC ANTIVENOM AND LOW-TEMPERATURE TO INHIBIT THE MYOTOXICITY AND NEUROMUSCULAR BLOCK INDUCED BY MICRURUS-NIGROCINCTUS VENOM
(Pergamon-elsevier Science LtdOxfordInglaterra, 1995)
A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A(2)-like proteins from viperid snake venoms
(Elsevier B.V., 2014-12-01)
Envenomation via snakebites is an important public health problem in many tropical and subtropical countries that, in addition to mortality, can result in permanent sequelae as a consequence of local tissue damage, which ...
Purification and characterization of myotoxin IV, a phospholipase A2 variant, from Bothrops asper snake venom
(1995)
A basic myotoxic protein was purified from Bothrops asper venom. Like other basic Bothrops myotoxins, myotoxin IV induces acute muscle damage after intramuscular injection in mice and disrupts negatively charged liposomes ...
Phospholipases A2 From Viperidae Snake Venoms: How do They Induce Skeletal Muscle Damage?
(Acta Chim. Slov., 58, 647–659, 2011, 2011)
Phospholipases A2 (PLA2s) are abundant components in snake venoms, which play important toxic roles. This review
focuses on group II PLA2s endowed with myotoxic effects, present in Viperidae venoms. These PLA2s are ...
Low-level laser therapy (LLLT) accelerates the sternomastoid muscle regeneration process after myonecrosis due to bupivacaine
(2017-03-01)
Background Because of its long-lasting analgesic action, bupivacaine is an anesthetic used for peripheral nerve block and relief of postoperative pain. Muscle degeneration and neurotoxicity are its main limitations. There ...
MYONECROSIS INDUCED BY SCORPION-VENOM
(Birkhauser Verlag AgBaselSuíça, 1973)