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Interactions between p-Akt and Smad3 in injured muscles initiate myogenesis or fibrogenesis
(Amer Physiological Soc, 2013-08-01)
In catabolic conditions such as aging and diabetes, IGF signaling is impaired and fibrosis develops in skeletal muscles. To examine whether impaired IGF signaling initiates muscle fibrosis, we generated IGF-IR+/- heterozygous ...
Histological changes induced by Polyglycolic-Acid (PGA) scaffolds seeded with autologous adipose or muscle-derived stem cells when implanted on rabbit bladder
(Landes Bioscience, 2014-04-01)
Purpose: To evaluate the morphological and histological changes induced by PGA scaffold seeded with autologous adipose or muscle derived stem cells implanted on rabbit bladder wall. Material and Methods: Adipose derived ...
Downhill exercise-induced changes in gene expression related with macrophage polarization and myogenic cells in the triceps long head of rats
(Springer, 2015-02-01)
Macrophages are one of the most heterogenic immune cells involved in skeletal muscle regeneration. After skeletal muscle damage, M1 phenotypes exhibit pro-inflammatory reaction. in a later stage, they are converted to M2 ...
Análise qualitativa dos efeitos da sonoforese com Arnica montana sobre o processo inflamatório agudo do músculo esquelético de ratos
(Universidade de São Paulo (USP), 2008-09-01)
Este estudo visou verificar o efeito da sonoforese com Arnica montana sobre a fase inflamatória aguda de uma lesão muscular. Para isso, 40 ratos Wistar machos, lesados cirurgicamente, foram divididos em 4 grupos: controle ...
Morphological aspects and Cox-2 expression after exposure to 780-nm laser therapy in injured skeletal muscle: an in vivo study
(Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia, 2014-10-01)
Background:The effectiveness of low-level laser therapy in muscle regeneration is still not well known. Objective: To investigate the effects of laser irradiation during muscle healing.Method: For this purpose, 63 rats ...
Comparison of treatments of peripheral arterial disease with mesenchymal stromal cells and mesenchymal stromal cells modified with granulocyte and macrophage colony-stimulating factor
(Informa Healthcare, 2013-07-01)
Background aims. Granulocyte macrophage-colony stimulating factor (GM-CSF) promotes vessel formation through several molecular signaling pathways. Mesenchymal stromal cells (MSCs) have an important role in neovasculogenesis ...
Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis
(Oxford University Press, 2010-03-15)
The nuclear poly(A)-binding protein 1 (PABPN1) is a ubiquitously expressed protein that plays a critical role in polyadenylation. Short expansions of the polyalanine tract in the N-terminus of PABPN1 lead to oculopharyngeal ...
A creatina como suplemento ergogênico para atletas
(Pontifícia Universidade Católica de Campinas, 2002-01-01)
Several researches on creatine have been done due to its potential effects on the physical performance of athletes involved in high intensity, short duration and intermittent exercises with short periods of recovery. ...