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Animal models in chronic obstructive pulmonary disease-an overview
(Informa Healthcare, 2014-08-01)
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airway obstruction resultant from an augmented inflammatory response of the respiratory tract to noxious particles and gases. Previous reports ...
Histological and histomorphometrical alterations of the periodontal ligament in gerbils submitted to teeth extraction
(2008-08-01)
This study verified the effect of unilateral teeth extraction on the periodontal ligament in gerbils (Meriones unguiculatus). Ten adult male gerbils weighing about 50 g had induced occlusal alterations by upper left molar ...
Infarto do miocárdio experimental em ratos: Análise do modelo
(2009-10-01)
One of the most often used strategies to study the physiopathological alterations caused by coronary occlusion is the use of the experimental infarction model in rats. Among other factors, this is due to the similarities ...
Gelatinous polyethylene in the treatment of the anophthalmic cavity
(2002-08-23)
PURPOSE: Gelatinous polyethylene (GP) has been used as an orbital implant to evaluate volume maintenance and tissue reaction in the anophthalmic socket in a rabbit model. METHODS: Twenty-eight Norfolk white rabbits underwent ...
Effect of topical application of 5-FU on the corneoscleral limbus of rabbits
(2007-04-01)
• Aim: To observe the effects of topical application of 5-fluorouracil (5-FU) on the rabbits corneal limbus. • Methods: 5-FU was applied topically to the corneoscleral region of rabbits eyes. The animals were sacrificed ...
Acellular dermal tissue study: an ultrastructural evaluation of human and porcine derived tissues in a rat model
(2004-07-01)
The purpose of this study was to evaluate the host response of a human and a porcine derived acellular dermal tissue (ADT) implanted in the subcutaneous tissue of a rat model. Two subcutaneous pockets were surgically created ...
Experimental models of sepsis and their clinical relevance
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Sepsis remains a major cause of morbidity and mortality mainly because of sepsis-induced multiple organ dysfunction. In contrast to preclinical studies, most clinical trials of promising new treatment strategies for sepsis ...