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Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis
(2006-04-01)
The recent appreciation of the role played by endogenous counterregulatory mechanisms in controlling the outcome of the host inflammatory response requires specific analysis of their spatial and temporal profiles. In this ...
B-1 cell participation in T-cell-mediated alloimmune response
(Elsevier B.V., 2010-04-01)
B-1 and B cells are important producers of natural antibodies in mice and humans and, therefore, are considered as the first line of defense against pathogens. Because of that, their role in T-cell-mediated immune responses ...
Immunohistochemical evaluation of prostaglandin E2 and vascular endothelial growth factor in canine cutaneous mast cell tumours
(Wiley-Blackwell Publishing, Inc, 2010-03-01)
Vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE-2) appear to play a critical role in tumour neovascularization. In this study, we have investigated the expression of VEGF and PGE-2 in 53 canine cutaneous ...
Cordia verbenacea and secretion of mast cells in different animal species
(Elsevier B.V., 2011-05-17)
Ethnopharmacology relevance: Different plant species from Cordia genera are used in folk medicine as anti-inflammatory medication throughout the tropical and subtropical regions of the world. In Brazil, Cordia verbenacea ...
The potentiation of the histamine release induced by adenosine in mast cells from guinea pig lung and heart: Sharp dependence on the time of preincubation
(Academic Press Ltd, 2000-03-01)
We studied here the effect of a wide range of adenosine concentration and time of preincubation, on the histamine release induced in the guinea pig mast cells by different stimulus. Adenosine (10(-5)-10(-3) M) potentiated ...
Histamine release induced by glucose (mannose)-specific lectins isolated from Brazilian beans. Comparison with concanavalin A
(1994-06-21)
The histamine releasing properties of glucose (mannose)-specific lectins isolated from Brazilian beans was examined. The Canavalia brasiliensis, Dioclea rostrata, and Dioclea virgata lectins induced histamine release in ...
Mineral trioxide aggregate stimulates macrophages and mast cells to release neutrophil chemotactic factors: role of IL-1 beta, MIP-2 and LTB4
(Mosby-elsevier, 2010-03-01)
Objective. In the present study, the role of macrophages and mast cells in mineral trioxide aggregate (MTA)-induced release of neutrophil chemotactic factor was investigated.Study design. MTA suspension (50 mg/mL) was ...
PHARMACOLOGICAL EVALUATION OF THE INHIBITORY EFFECT OF EXTRACTS FROM ANCHIETIA-SALUTARIS ON THE HISTAMINE-RELEASE INDUCED IN THE RAT AND THE GUINEA-PIG
(Karger, 1994-01-01)
The tea made with leaves and stems of plant Anchietia salutaris is traditionally used in Brazil to treat allergies. We examined the effects of a crude aqueous extract and of purified fractions of this plant on the histamine ...
Mast cells modulate the inflammatory process in endotoxin-induced uveitis
(Molecular Vision, 2011-05-08)
Purpose: To investigate the role of mast cells and annexin-A1 (Anxa1) in endotoxin-induced uveitis (EIU).Methods: EIU was induced by injection of lipopolysaccharide (LPS) into the paws of rats, which were then sacrificed ...
Effects of ethanol, acetaldehyde, and acetic acid on histamine secretion in guinea pig lung mast cells
(Elsevier B.V., 2000-02-01)
We studied the direct effects of ethanol and its metabolites on the guinea pig lung mast cell, and the alterations caused in the histamine release induced by different stimuli. Guinea pig lungs cells dispersed by collagenase ...