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Endogenous annexin-A1 negatively regulates mast cell-mediated allergic reactions
(2019-01-01)
Mast cell stabilizers like cromoglycate and nedocromil are mainstream treatments for ocular allergy. Biochemical studies in vitro suggest that these drugs prevent mast cell degranulation through the release of Annexin-A1 ...
Effect of propolis extract on guines pig lung mast cell
(Centro de Estudos de Venenos e Animais Peçonhentos, 2005-03)
The direct effect of ethanolic extract of propolis on guinea pig lung cell suspension containing mast cells, as well as its influence on the histamine release induced by antigen (ovoalbumin 10 mug/ml) and ionophore A 23187 ...
A comparison between the concentration of mast cells in squamous cell carcinomas of the skin and oral cavity
(SOC BRASILEIRA DERMATOLOGIA, 2010)
FUNDAMENTS: The lethality of squamous cell carcinomas (SCC) of the skin is considered low. SCC in the mouth is usually associated with poor prognosis. Current evidence suggests that mast cells in the normal tissue contribute ...
Mast cell-associated alveolar inflammation in patients with atopic uncontrolled asthma
(MOSBY-ELSEVIER, 2011)
Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is ...
Mast cells and MMP-9 in the lamina propria during eruption of rat molars: quantitative and immunohistochemical evaluation
(Wiley-Blackwell, 2010-08-01)
During the active tooth eruption process, structural changes in the lamina propria are necessary to provide extracellular matrix remodelling and for the establishment of the eruptive pathway. A large number of resident ...
Pharmacological modulation of allergic inflammation in the rat airways and association with mast cell heterogeneity
(Elsevier B.V., 2001-08-24)
Administration of ovalbumin by aerosol to sensitised rats produced a rapid (15 min) protein exudation in different airway tissues, as determined by Evans blue staining. This was associated with marked mast cell degranulation ...
The Lectin ArtinM Induces Recruitment of Rat Mast Cells from the Bone Marrow to the Peritoneal Cavity
(PUBLIC LIBRARY SCIENCE, 2010)
Background: The D-mannose binding lectin ArtinM is known to recruit neutrophils, to degranulate mast cells and may have potential therapeutic applications. However, the effect of ArtinM on mast cell recruitment has not ...
Differential effect of plant lectins on mast cells of different origins
(Associação Brasileira de Divulgação Científica (ABRADIC), 2005-06-01)
Histamine release induced by plant lectins was studied with emphasis on the carbohydrate specificity, external calcium requirement, metal binding sites, and mast cell heterogeneity and on the importance of antibodies bound ...
Immunohistochemical evaluation of prostaglandin E2 and vascular endothelial growth factor in canine cutaneous mast cell tumours
(Wiley-Blackwell Publishing, Inc, 2010-03-01)
Vascular endothelial growth factor (VEGF) and prostaglandin E2 (PGE-2) appear to play a critical role in tumour neovascularization. In this study, we have investigated the expression of VEGF and PGE-2 in 53 canine cutaneous ...
Mineral trioxide aggregate stimulates macrophages and mast cells to release neutrophil chemotactic factors: role of IL-1 beta, MIP-2 and LTB4
(Mosby-elsevier, 2010-03-01)
Objective. In the present study, the role of macrophages and mast cells in mineral trioxide aggregate (MTA)-induced release of neutrophil chemotactic factor was investigated.Study design. MTA suspension (50 mg/mL) was ...