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Neosaxitoxin inhibits the expression of inflammation markers of the M1 Phenotype in macrophages
(MDPI, 2020)
Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide ...
The acute-phase response of the liver in relation to thyroid hormone-induced redox signaling
(ELSEVIER, 2006-05-01)
Recently, we reported that 3,3,5-triiodothyronine (T-3) induces the expression of redox-sensitive genes as a nongenomic mechanism of T3 action. In this study, we show that T3 administration to rats (daily doses of 0. 1 ...
Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes Involved in Cell Adhesion and Motility
(2012-02-10)
Runt-related transcription factors (RUNX1, RUNX2, and RUNX3) are key lineage-specific regulators of progenitor cell growth and differentiation but also function pathologically as cancer genes that contribute to tumorigenesis. ...
Role of dietary alpha- and gamma-tocopherol from Rosa mosqueta oil in the prevention of alterations induced by high-fat diet in a murine model
(Elsevier, 2018)
Objective: The aim of this study was to evaluate the contribution of tocopherols present in Rosa mosqueta oil (RM) in the prevention of high-fat diet (HFD)-induced alterations.
Methods: Male C57 BL/6 J mice (n = 9/group) ...
Efecto de metformina sobre la expresión del factor de necrosis tumoral-a, los receptores Toll-like 2/4 y la PCR ultra sensible en sujetos obesos con diabetes tipo 2
(2012)
Background: The pharmacological action of metformin goes beyond mere
glycemic control, decreasing markers of inflammation and contributing to the
reduction of oxidative stress. Aim: To evaluate biochemical, anthropometric ...
Rosa mosqueta oil prevents oxidative stress and inflammation through the upregulation of PPAR-alpha and NRF2 in C57BL/6J mice fed a high-fat diet
(American Society for Nutrition, 2017)
Background: Rosa mosqueta (RM) oil is characterized by high concentrations of antioxidants and alpha-linolenic acid (ALA; 18: 3n-3). We have previously demonstrated in male C57BL/6J mice that RM decreases hepatic steatosis, ...
Melanoma maligno palpebral en un equino: reporte de un caso
(Universidad de los Llanos, 2012-06-30)
El objetivo de este trabajo fue relatar un caso de melanoma en un equino cruceto cuarto de milla, macho, de 10 años de edad, color moro, el cual fue llevado a la clínica de la Universidad de los Llanos por una masa en el ...
Decreased invariant natural killer T-cell-mediated antitumor immune response in patients with gastric cancer
(Wiley, 2020)
Gastric cancer (GC) is the third most common cause of cancer-related death worldwide. Invariant natural killer T (iNKT) cells are innate-like cytotoxic T lymphocytes involved in tumor immune surveillance. They can be ...
Preeclampsia, problema de salud pública latente: Etiología genética y molecular
(2010)
La preeclampsia (PE) es un trastorno que afecta la gestación humana, constituye la principal causa de mortalidad materna en Colombia y se asocia al nacimiento de niños con bajo peso al nacer. La mayoría de los casos de ...