Buscar
Mostrando ítems 41-50 de 191
Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice
(Elsevier, 2018-09)
Consumption of diets high in fat and/or fructose content promotes tissue inflammation, oxidative stress, and insulin resistance, activating signals (e.g. NF-κB/JNK) that downregulate the insulin cascade. Current evidence ...
Metformin reduces insulin resistance and the tendency toward hyperglycaemia and dyslipidaemia in dogs with hyperadrenocorticism
(University of Tripoli. Faculty of Veterinary Medicine, 2018-06)
Hypercortisolism induces a state of insulin resistance that can occur concurrently with fasting hyperglycaemia,dyslipidaemia and diabetes mellitus. Metformin reduces hepatic glucose production and insulin resistance of ...
(-)-Epicatechin prevents TNFα-induced activation of signaling cascades involved in inflammation and insulin sensitivity in 3T3-L1 adipocytes
(Elsevier Science Inc, 2012-11)
Obesity is major public health concern worldwide and obese individuals exhibit a higher risk of chronic diseases such as type 2 diabetes. Inflammation plays a significant role in metabolic regulation and mounting evidence ...
One-year treatment with gonadotropin-releasing hormone analogues does not affect body mass index, insulin sensitivity or lipid profile in girls with central precocious puberty
(De Gruyter, 2019-01-30)
Background: Puberty is associated with a physiological decline in insulin sensitivity (IS). Overweight (OW) and obesity (OB) are common among girls with central precocious puberty (CPP). CPP is considered a risk factor for ...
Grape pomace and grape pomace extract improve insulin signaling in high-fat-fructose fed rat-induced metabolic syndrome
(Royal Society of Chemistry, 2016-03)
In this study the effect of diet supplementation with grape pomace (GP) and grape pomace extract (GPE) on insulin sensitive tissues (adipose, liver and muscle) was evaluated in an experimental model of metabolic syndrome ...
Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity and insulin resistance
(American Diabetes Association, 2015-01)
Accumulation evidence links obesity-induced inflammation as an important contributor to the development of insulin resistance which plays a key role in the pathophysiology of obesity-related diseases such as type 2 diabetes ...
Fructose-rich diet-induced abdominal adipose tissue endocrine dysfunction in normal male rats
(Humana Press, 2009-04)
We have currently studied the changes induced by administration of a fructose-rich diet (FRD) to normal rats in the mass and the endocrine function of abdominal (omental) adipose tissue (AAT). Rats were fed ad libitum a ...
Antioxidant treatment prevents the development of fructose-induced abdominal adipose tissue dysfunction
(Portland Press, 2013-02)
In the present study, we tested the effect of OS (oxidative stress) inhibition in rats fed on an FRD [fructose-rich diet; 10% (w/v) in drinking water] for 3 weeks. Normal adult male rats received a standard CD (commercial ...
Impact of transient correction of increased adrenocortical activity in hypothalamo-damaged, hyperadipose female rats
(Springer Nature, 2006)
To explore the effects of transient correction of enhanced corticoadrenal activity in monosodium L-glutamate (MSG)-damaged female rats on peripheral insulin sensitivity and in vitro retroperitoneal (RP) adipocyte function.
Dietary fish oil ameliorates adipose tissue dysfunction in insulin-resistant rats fed a sucrose-rich diet improving oxidative stress, peroxisome proliferator-activated receptor γ and uncoupling protein 2
(Royal Society of Chemistry, 2018-04)
This work aimed to assess the possible beneficial effects of dietary fish oil (FO) on the preexisting adipose tissue dysfunction through the improvement or reversion of the mechanisms underlying oxidative stress and ...