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Fisiologia do eixo GH-sistema IGF
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008)
O crescimento, principal característica da infância e da adolescência, apresenta padrão semelhante na maioria dos indivíduos. A herança genética e os componentes do eixo GH-IGF são os fatores que diretamente influenciam ...
Hepatic mRNA expression and plasma levels of insulin-like growth factor-I (IGF-I) in broiler chickens selected for different growth rates
(Sociedade Brasileira de Genética, 2004-01-01)
The hepatic expression and plasma concentrations of IGF-I were investigated in three broiler chicken strains selected for different growth rates (HP-Hubbard-Pettersen, a fast growing strain; NN-Naked-neck, a strain with ...
Impact of hypoxia on IGF-I, IGF-II, IGFBP-3, ALS and IGFBP-1 regulation and on IGF1R gene expression in children
(CHURCHILL LIVINGSTONEEDINBURGH, 2012)
Hypoxia is one of many factors involved in the regulation of the IGF system. However, no information is available regarding the regulation of the IGF system by acute hypoxia in humans. Objective: The aim of this study was ...
Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis
(BIOSCIENTIFICA LTDBRISTOL, 2016)
Fsh Stimulates Spermatogonial Proliferation and Differentiation in Zebrafish via Igf3
(Endocrine Soc, 2015-10-01)
Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a steroid-independent manner the number ...
Feed restriction and insulin-like growth factor-I (IGF-I) affect the oocyte maturation in matrinxã Brycon amazonicus
(2017-01-01)
Summary The feeding and nutrition of breeders are crucial aspects in the reproductive process. During the maturation period, metabolic changes occur aiming at mobilizing energy for growth and follicular development. The ...
Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
(Karger, 2017)
Background: The growth-promoting effects of IGF-I is mediated through the IGF-I receptor (IGF1R), a widely expressed cell-surface tyrosine kinase receptor. IGF1R copy number variants (CNV) can cause pre- and postnatal ...
New insights into IGF-1 signaling in the heart
(Elsevier, 2014)
Insulin-like growth factor 1 (IGF-1) signaling regulates
contractility, metabolism, hypertrophy, autophagy,
senescence, and apoptosis in the heart. IGF-1 deficiency
is associated with an increased risk of cardiovascul ...
Differential expression of members of the IGF system in OPU-derived oocytes from Nelore (Bos indicus) and Holstein (Bos taurus) cows
(2013-05-01)
The insulin-like growth factor (IGF) system is related to quality of oocytes and embryos. The aim of this study was to investigate the mRNA levels of IGF1 and IGF2 and their receptors, IGFR1 and IGFR2, as well as IGFBP2, ...
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
(European Society of Cardiology, 2012)
Aims Insulin-like growth factor 1 (IGF-1) is known to exert cardioprotective actions. However, it remains unknown if
autophagy, a major adaptive response to nutritional stress, contributes to IGF-1-mediated cardioprotec ...