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Self-assembling functional programmable protein array for studying protein-protein interactions in malaria parasites
(2018)
Background: Plasmodium vivax is the most widespread malarial species, causing significant morbidity worldwide. Knowledge is limited regarding the molecular mechanism of invasion due to the lack of a continuous in vitro ...
Dissection of the 16S rRNA binding site for ribosomal protein S4
(Elsevier Science Publishers B. V., 1990)
The ribosomal protein S4 from Escherichia coli is essential for initiation of assembly of 30S ribosomal subunits. We have undertaken the identification of specific features required in the 16S rRNA for S4 recognition by ...
Topological properties and in vitro identification of essential nodes of the Paclitaxel and Vincristine interactomes in PC-3 cells
(2019)
Background: Microtubule-targeting agents (MTAs) disrupt microtubule dynamics, thereby inducing apoptosis via mitochondrial pathway activation through the modulation in the expression of the Bcl-2 family. Methods: To describe ...
Stability of quinoa flour proteins (Chenopodium quinoa Willd.) during storage
(WILEY-BLACKWELL PUBLISHING, 2009-10)
P>The amino acid composition and the physicochemical and functional properties of quinoa flour proteins (QFP) were evaluated during storage (at 20, 30 and 40 degrees C). Quinoa flour showed a protein content of 14.2 +/- ...
Role of the MAGUK Protein Family in Synapse Formation and Function
(WILEY-BLACKWELL, 2012-01)
Synaptic function is crucially dependent
on the spatial organization of the presynaptic and
postsynaptic apparatuses and the juxtaposition of both
membrane compartments. This precise arrangement is
achieved by a protein ...
Cystein-Serine-Rich Nuclear Protein 1, Axud1/Csrnp1, Is Essential for Cephalic Neural Progenitor Proliferation and Survival in Zebrafish
(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2009-04-15)
The CSRNP (cystein-serine-rich nuclear protein) family has been conserved from Drosophila to human.
Although knockout mice for each of the mammalian proteins have been generated, their function during
vertebrate development ...
Converging pathways in the occurrence of endoplasmic reticulum (er) stress in Huntington's disease
(2011)
A variety of neurological diseases including Huntington's disease (HD), Alzheimer's disease and Parkinson's disease share common neuropathology, primarily featuring the presence of abnormal protein inclusions containing ...
The protein kinase cdk5: Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology
(2001)
A set of different protein kinases have been involved in tau phosphorylations, including glycogen synthase kinase 3b (GSK3b), MARK kinase, MAP kinase, the cyclin-dependent kinase 5 (Cdk5) system and others. The latter ...
Human intestinal mucus proteins isolated by transanal irrigation and proctosigmoidoscopy
(Universidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Química, 2014-09-01)
Human intestinal mucus essentially consists of a network of Mucin2 glycoproteins embedded in many lower molecularweight proteins. This paper contributes to the proteomic study of human intestinal mucus by comparing two ...