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Padronização de parâmetros eletrocardiográficos de cães da raça Golden Retriever clinicamente sadios
(RIO DE JANEIRO, 2010)
A distrofia muscular de Duchenne (DMD) em humanos é uma alteração neuromuscular hereditária, de caráter recessivo, ligada ao cromossomo X e causada pela ausência ou disfunção da distrofina. Clinicamente, caracteriza-se por ...
LONG-TERM THERAPY WITH DEFLAZACORT DECREASES MYOCARDIAL FIBROSIS IN mdx MICE
(John Wiley & Sons IncHobokenEUA, 2009)
Atrophic Cardiac Remodeling Induced by Taurine Deficiency in Wistar Rats
(Public Library Science, 2012-07-23)
Introduction: Micronutrient deficiency is observed in heart failure patients. Taurine, for example, represents 50% of total free amino acids in the heart, and in vivo studies have linked taurine deficiency with ...
Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells
(Public Library of Science, 2015-10-09)
Chronic Chagas cardiomyopathy caused by Trypanosoma cruzi is the result of a pathologic process starting during the acute phase of parasite infection. Among different factors, the specific recognition of glycan structures ...
Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
(Baishideng Publishing Group, 2014-07)
Neuregulin-1 (NRG1) signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis, and it plays an essential role in maintaining the myocardial architecture during adulthood. The ...
Frataxin deficiency in neonatal rat ventricular myocytes targets mitochondria and lipid metabolism
(Elsevier, 2014-08)
Friedreich ataxia (FRDA) is a hereditary disease caused by deficient frataxin expression. This mitochondrial protein has been related to iron homeostasis, energy metabolism, and oxidative stress. Patients with FRDA experience ...