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Mostrando ítems 11-20 de 1846
Adrenal Rest Tumor of the Liver Causing Cushing’s Syndrome: Treatment withKetoconazole preceding an Apparent Surgical Cure
(1985)
Ketoconazole, an imidazole derivative known to inhibit cytochrome P450-dependent adrenal enzymes was given to a patient with a functioning adrenal rest tumor of the liver in preparation for surgery. The drug was administered ...
Certain large forms of circulating immunoreactive human growth hormone are in fact immunoglobulins
(1990)
To explain frequent discordances between serum GH levels and clinical manifestation of acromegaly, we investigated the possibility that certain immunoglobulins G (IgGs) might be responsible for the displacement of [125I]human ...
Low molecular weight thyroglobulin leading to a goiter in a 12-year-old girl
(1984)
We characterized the abnormal thyroglobulin (TG) in the thyroid and serum of a 12-yr-old girl with a large sporadic multinodular goiter first noted at age 4 yr. She developed normallyand had no clinical evidence of ...
Enhanced skeletal muscle lipid oxidative efficiency in insulin-resistant vs insulin-sensitive nondiabetic, nonobese humans
(2013)
Context: Skeletal muscle insulin resistance is proposed to result from impaired skeletal muscle lipid oxidative capacity. However, there is no evidence indicating that muscle lipid oxidative capacity is impaired in healthy ...
Up-regulation of PPAR-γ mRNA expression in the liver of obese patients: An additional reinforcing lipogenic mechanism to SREBP-1c induction
(2011)
Introduction: Triglyceride accumulation in the liver is an early feature in the development of nonalcoholic fatty liver disease (NAFLD) associated with human obesity, which is a multifactorial syndrome and whose underlying ...
Adrenal function during childhood and puberty in daughters of women with polycystic ovary syndrome
(Endocrine Society, 2009)
Context: In some patients, PCOS may develop as a consequence of an exaggerated adrenarche during pubertal development. Objective: The aim of the study was to assess adrenal function during childhood and pubertal development ...
Interrelationships among serum thyroxine, triiodothyronine, reverse triiodothyronine, and thyroid-stimulating hormone in iodine-deficient pregnant women and their offspring: Effects of iodine supplementation
(1981)
Adaptation to iodine deficiency (ID) requires changes in thyroid and pituitary function that have been well characterized in animals. The present studies were undertaken to analyze the relationships between serum thyroid ...
Fasting and post-glucose ghrelin levels in SGA infants: Relationships with size and weight gain at one year of age
(2002)
Wide ranges in postnatal weight gain are seen in infants born small for gestational age (SGA); most show some catch-up growth and this may be driven by increased appetite. Ghrelin, the natural ligand of the GH secretagogue ...
Human lactational response to oral thyrotropin releasing hormone
(1976)
Several studies were designed to evaluate the effect of oral TRH on prolactin (PRL) secretion and mammary function in nursing women. Initially, efficacy was studied in nursing women following 5 mg TRH. PRL levels rose to ...