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Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release
(WILEY-BLACKWELL, 2011)
BACKGROUND AND PURPOSE We investigated the effect of the phosphodiesterase-5 inhibitor, tadalafil, on the acute hypernociception in rat models of arthritis. EXPERIMENTAL APPROACH Rats were treated with either an intra-articular ...
Blockade of the chemokine receptor CXCR2 ameliorates adjuvant-induced arthritis in rats
(NATURE PUBLISHING GROUP, 2008)
Background and purpose: Chemokine receptors CXCR1 and CXCR2 may mediate influx of neutrophils in models of acute and chronic inflammation. The potential benefits of oral administration of a CXCR1/2 inhibitor, DF 2162, in ...
Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils
(ELSEVIER SCIENCE INC, 2011)
Short chain fatty acids (SCFAs) are fermentation products of anaerobic bacteria. More than just being an important energy source for intestinal epithelial cells, these compounds are modulators of leukocyte function and ...
Dietary Free Oleic and Linoleic Acid Enhances Neutrophil Function and Modulates the Inflammatory Response in Rats
(SPRINGER HEIDELBERG, 2010)
The high ingestion of oleic (OLA) and linoleic (LNA) acids by Western populations, the presence of inflammatory diseases in these populations, and the importance of neutrophils in the inflammatory process led us to investigate ...
Cytokine inhibition and time-related influence of inflammatory stimuli on the hyperalgesia induced by the nucleus pulposus
(SPRINGERNEW YORK, 2012)
The symptoms of lumbar disc herniation, such as low back pain and sciatica, have been associated with local release of cytokines following the inflammatory process induced by the contact of the nucleus pulposus (NP) with ...
Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic rats
(2010-07-28)
Abstract
Background
Clinical and experimental data suggest that the inflammatory response is impaired in diabetics and can be modulated by insulin. The present study was ...
Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic rats
(2010-07-28)
Abstract
Background
Clinical and experimental data suggest that the inflammatory response is impaired in diabetics and can be modulated by insulin. The present study was ...
Insulin modulates cytokine release and selectin expression in the early phase of allergic airway inflammation in diabetic rats
(2010)
Abstract
Background
Clinical and experimental data suggest that the inflammatory response is impaired in diabetics and can be modulated by insulin. The present study was undertaken to investigate the role of insulin on ...
Role of renin-angiotensin system and oxidative stress on vascular inflamation in insulin resistence model
(Hindawi Publishing Corporation, 2013-01)
(1) is study aims to demonstrate the causal involvement of renin angiotensin system (RAS) and oxidative stress (OS) on vascular inammation in an experimental model of metabolic syndrome (MS) achieved by fructose ...