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Mostrando ítems 31-40 de 173
Treating Metastatic Brain Cancers With Stem Cells
(Frontiers Media S.A., 2021-11-24)
Stem cell therapy may present an effective treatment for metastatic brain cancer and glioblastoma. Here we posit the critical role of a leaky blood-brain barrier (BBB) as a key element for the development of brain metastases, ...
A direct high-throughput in Cell-ELISA for measuring infectivity of cytopathic and non-cytopathic bovine viral diarrhoea virus strains applied to the assessment of antiviral activity
(Elsevier Science, 2018-10)
Low-cost high-throughput methods applicable to any virus strain are required for screening antiviral compounds against multiple field strains. Colorimetric cell-viability assays are used for this purpose as long as the ...
Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways
(Pergamon-Elsevier Science Ltd, 2018-04)
Aims Linalool is a plant-derived monoterpene with anticancer activity, however its mechanisms of action remain poorly understood. The aim of this work was to elucidate the anticancer mechanisms of action of linalool in ...
Oxidative Response and Micronucleus Centromere Assay in HEp-2 Cells Exposed to Fungicide Iprodione
(American Chemical Society, 2019-04)
The fungicide agents are a key component in the fruits and vegetables production. The Iprodione residues are one of the pesticide more frequently found in food products. The available data about the cytotoxicity of iprodione ...
EVALUACIÓN DE LA CAPACIDAD FÉRTIL DE LA RETAMA (Spartium junceum)RETAMA CAPACITY ASSESSMENT FERTILE (Spartium junceum)
(Universidad Nacional del Centro del Peru, 2022)
Effect of heat treatment and spray drying on lactobacilli viability and resistance to simulated gastrointestinal digestion
(Elsevier, 2012-10)
Commercial probiotic bacteria are delivered mainly as frozen or freeze-dried cultures. However, spray drying is a lower cost technology that could be used for the production of probiotic cultures. In this work we aimed at ...
Development of a potentially probiotic food through fermentation of Andean tubers
(Elsevier Science, 2016-09)
With the aim to obtain a non-dairy solid probiotic product, three different Andean tubers -oca (Oxalis tuberosa), papalisa (Ullucus tuberosus) and potato (Solanum tuberosum spp andigena)- were assessed as fermentation ...
Coculture of porcine cumulus-oocyte complexes with porcine luteal cells during IVM: Effect on oocyte maturation and embryo development
(Csiro Publishing, 2020-11)
Coculture with somatic cells is an alternative to improve suboptimal in vitro culture conditions. In pigs, IVF is related to poor male pronuclear formation and high rates of polyspermy. The aim of this study was to assess ...
Metformin and glucose starvation decrease the migratory ability of hepatocellular carcinoma cells: targeting AMPK activation to control migration
(Nature Publishing Group, 2019-02)
Hepatocellular carcinoma (HCC) is a highly metastatic cancer with very poor prognosis. AMP activated kinase (AMPK) constitutes a candidate to inhibit HCC progression. First, AMPK is downregulated in HCC. Second, glucose ...
Benzoxaboroles as dynamic covalent receptors for bioconjugation and transport of nucleosides and related drugs: proof of action in HeLa cells
(Academic Press Inc Elsevier Science, 2019-06)
In this work we describe not previously explored binding studies on the reversible interaction of benzoxaborole with ligands of medical and pharmaceutical interest such as nucleosidic drugs gemcitabine and capecitabine, ...