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Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside
(Elsevier, 2018-04-25)
Conjugation to carrier proteins is a way to improve the immunogenicity of peptides. Such is the case for peptides mimicking carbohydrate tumor-associated antigens in cancer vaccine development. The most used protein for ...
Tax Secretion From Peripheral Blood Mononuclear Cells and Tax Detection in Plasma of Patients With Human T-Lymphotropic Virus-Type 1-Associated Myelopathy/Tropical Spastic Paraparesis and Asymptomatic Carriers
(Wiley-Blackwell, 2016)
Human T-lymphotropic virus-type 1 (HTLV-1) is the etiologic agent of the neurologic disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Tax viral protein plays a critical role in viral pathogenesis. ...
Novel strategies for the buccal delivery of macromolecules
(Informa Healthcare, 2014)
For years now, the delivery of small molecules through the buccal mucosal route has been described in the literature, but it has only been over the past decade that investigations into macromolecule delivery via the buccal ...
Development and Characterization of Florfenicol-Loaded BSA Nanoparticles as Controlled Release Carrier
(Springer New York LLC, 2019)
Florfenicol (FLO) is a broad-spectrum fluorinated antibiotic used for the treatment of bacterial diseases such as bovine respiratory disease (BRD) in cattle. FLO is a poorly soluble drug in aqueous solution, and its ...
Protein-coated nanoparticles embedded in films as delivery platforms
(Royal Pharmaceutical Society, 2013)
Objectives This work aimed to evaluate the performance of nanoparticle-loaded
films based on matrices of polymethacrylates and hydroxypropylmethylcellulose
(HPMC) intended for delivery of macromolecules.
Methods Lysozyme ...
Polimorfismo de la proteína ligante de ácidos grasos intestinal (FABP2), obesidad e insulina resistencia
(2006)
The genetic components of insulin-resistance, diabetes and obesity
have been largely studied. These conditions are determined by multiple polygenic and
environmental factors. Certain candidate genes, that have common ...
Novel edible toys as iron carrier to prevent iron deficiency of postweaned pigs
(Elsevier, 2021)
The current preventive treatment for iron deficiency in pigs is inefficient, resulting in a high prevalence of iron-deficient or anemic postweaned pigs. The aim of this study was to develop and characterize edible toys ...
FMR1 mRNA from full mutation alleles is associated with ABC-C-FX scores in males with fragile X syndrome
(Nature, 2020)
Fragile X syndrome (FXS) is caused by a hypermethylated full mutation (FM) expansion with >= 200 CGG repeats, and a decrease in FMR1 mRNA and its protein. However, incomplete silencing from FM alleles has been associated ...
El sistema de la proteína C activada en el cuadro séptico
(Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud, 2011-03-01)
Fragile X Syndrome.
(2015-02-10)
Fragile X Syndrome (FXS) is a genetic disease due to a CGG
trinucleotide expansion, named full mutation (greater than 200
CGG repeats), in the FMR1 gene locus Xq27.3; which leads to an
hypermethylated region in the gene ...